Systematic fractionation of a fruit extract from Argentine Melia azedarach L., which was monitored by an insect antifeedant bioassay, led to the isolation of meliartenin, a limonoid antifeedant, which existed as a mixture of two interchangeable isomers. At 4 microg/cm2 and 1 microg/cm2, the isomeric mixture was as active as azadirachtin in strongly inhibiting the larval feeding of Epilachna pae...

Diabetes type 2 is associated with impaired insulin production and increased insulin resistance. Treatment with antidiabetic drugs and insulin strives for normalizing glucose homeostasis. In Ethiopian traditional medicine, plant extracts of Melia azedarach are used to control diabetes mellitus and various gastrointestinal disorders. The objective of this study was to clarify the antidiabetic ef...

A crude acetone extract and oil of ripe fruits from Melia azedarach L. were evaluated against the 2nd and 4th instar larvae of Spodoptera littoralis (Boisd.) (Lepidoptera: Noctuidae). Both oil and extract exhibited highly significant growth inhibition at all concentrations tested, while the oil of M. azedarach recorded higher insecticidal activity against both instars than the crude extract. GC...

The antioxidant activity of the melia azedarach was investigated in rats with ethanol-induced erythrocyte damage. Chronic administration of ethanol (20% w/v, 2 g/kg.p.o.,daily for four weeks) increased the level of lipid peroxidation (LPO), decreased the activity of superoxide dismutase (SOD) and catalase and reduced the content of glutathione (GSH). The concurrent treatment of ethanol-admini...

the antioxidant activity of the melia azedarach was investigated in rats with ethanol-induced erythrocyte damage. chronic administration of ethanol (20% w/v, 2 g/kg.p.o.,daily for four weeks) increased the level of lipid peroxidation (lpo), decreased the activity of superoxide dismutase (sod) and catalase and reduced the content of glutathione (gsh). the concurrent treatment of ethanol-administ...

background & aim: aphids are of serious pests and vectors of multitude of viral diseases of field crops, vegetables, ‎and greenhouse crops. they have displayed a remarkable ability to establish resistance to ‎almost every insecticide with which it has been treated. to reduce the damage of these pests ‎and dependence on the sometimes unwise use of synthetic pesticides in crop and vegetable ‎...