OBJECTIVE To evaluate discordancy between clinical predictions and lymphatic drainage patterns of primary cutaneous melanoma as determined by preoperative lymphoscintigraphy and intraoperative lymphatic mapping of sentinel lymph nodes (SLNs). DESIGN Before selective SLN dissection, 226 consecutive patients with melanoma underwent preoperative lymphoscintigraphy. SETTING Teaching hospital te...

The head and neck region, and especially the ear and its helix, is notorious for its ambiguous pattern of lymphatic drainage. Therefore, the primary nodal drainage basins in melanoma of the helix of the ear are often unpredictable. The aim of the study was to examine the value of sentinel lymph node biopsy in melanoma of the helix of the ear and to describe the natural history of the disease. F...

UNLABELLED The sentinel lymph node (SLN) is the first node in a lymph node basin to receive direct drainage from the primary tumour. However, in some cases, lymphoscintigraphy images demonstrate the presence of lymph nodes located in the area between the primary tumour and the first regional lymph node basin. These nodes are called in-transit nodes and have to be considered SLNs as well. AIM ...

BACKGROUND The head and neck have a rich lymphatic drainage and complex anatomy, which complicate sentinel lymph node (SLN) biopsy for melanoma. The incidence of regional recurrence after a negative SLN biopsy has been shown to be higher than that at other sites. Compounding factors in this scenario were analyzed to determine their impact on both SLN status and survival. METHODS A retrospecti...

OBJECTIVE Sentinel lymph node biopsy (SLNB) is a widely accepted method in the management of clinically localized cutaneous melanomas. The aim of this study was to report the results on patients scheduled for preoperative lymphoscintigraphy and SLNB for staging and further treatment planning. SUBJECTS AND METHODS Two hundred and one patients (115 male and 86 female, median age 57 years, range...

Basin morphometry is a means of numerically analysing or mathematically quantifying different aspects of a drainage basin. In the present study, morphometric analysis of the Baitarani basin has been carried out using earth observation data and geographical information system (GIS) techniques. The morphometric parameters considered for analyses include the linear, areal and relief aspects of the...

INTRODUCTION The objective of this study is to analyze our experience in the use of sentinel node biopsy (SNB) in melanoma and identify the predictive factors of positive SNB and multiple drainage. MATERIAL AND METHODS Retrospective study of patients who underwent SNB for melanoma between August of 2000 and February of 2013. RESULTS SNB was performed in 125 patients with a median of age of ...

Shape indices have been in use for several decades to describe the characteristics and hydrological properties of drainage basins. Due to the fractal behaviour of the basin boundary, perimeter-based shape indices depend on the scale at which they are determined. Therefore, these indices cannot objectively compare drainage basins across a range of scales and basin sizes. This paper presents an o...

The assessment of uncertainty is a major challenge in geomorphometry. Methods to quantify uncertainty in digital elevation models (DEM) are needed to assess and report derivatives such as drainage basins. While Monte-Carlo (MC) techniques have been developed and employed to assess the variability of second-order derivatives of DEMs, their application requires explicit error modelling and numero...

Oncologic staging of many solid organ malignancies involves an understanding of how cancers spread via the lymphatic system, and ultimately may involve evaluation of the primary nodal drainage basin by performing a sentinel lymph node biopsy. In the adult population, there are well established indications for sentinel lymph node biopsy in diseases like melanoma and breast cancer. However, its u...