In this research, the production possibility of TiC-Al2O3 nanocomposite, as a useful ceramic from commercially pure TiO2, aluminum powder and carbon black has been investigated. Routile (TiO2) with carbon black and aluminum were placed in a high energy ball mill and sampled during different milling times. Then, the activated powders were synthesized at different temperatures in an atmosphere co...

background: p2x4 receptor (p2x4r), a purinoceptor expressed in activated spinal microglia, plays a key role in the pathogenesis of neuropathic pain. spinal nerve injury induces up-regulation of p2x4r on activated microglia in the spinal cord, and blockade of this receptor can reduce neuropathic pain. the present study was undertaken to determine whether paroxetine, an inhibitor of p2x4r, could ...

Background: P2X4 receptor (P2X4R), a purinoceptor expressed in activated spinal microglia, plays a key role in the pathogenesis of neuropathic pain. Spinal nerve injury induces up-regulation of P2X4R on activated microglia in the spinal cord, and blockade of this receptor can reduce neuropathic pain. The present study was undertaken to determine whether paroxetine, an inhibitor of P2X4R, could ...

The effects of silica fume and sodium silicate-based activators (SFA SSA, respectively) with different Ms (SiO2/Na2O) values on the setting behavior, rheological, mechanical, microstructural properties alkali-activated slag cement (AASC) were investigated. Setting time test results showed that AASCs activated by SFA prolonged significantly an increase value opposite to SSA activation case. From...

BACKGROUND AND OBJECTIVES Mechanical stimulation and hormones act via interconnected signaling pathways to influence the function of bone cells. Estrogen receptor (ER) and β-catenin play important role in bone formation and have implicated in mechanotransduction in bone cells. To investigate the interaction between mechanotransduction and estrogenic signaling in mesenchymal stem cells (MSCs), t...

in this research, kinetics of carbothermic reduction of molybdenite in the presence of different amounts of sodium carbonate has been studied. mixed powders consisting of molybdenite, graphite and sodium carbonate with three mole-ratios of 1:4:2,1:4:3 and 1:4:4 were mechanically activated for 40 hours. the results of x-ray diffraction on activated samples showed that no reaction occurrs in diff...

Abstract Intradermally injected capsaicin induces secondary mechanical hyperalgesia and allodynia outside the primary (i.e., capsaicininjected) site. This secondary mechanical hypersensitivity is attributed to central sensitization in which reactive oxygen species (ROS) play a key role. We examined whether ROS would be differentially involved in secondary mechanical hyperalgesia and allodynia u...