Measles continues to be a major cause of childhood morbidity and mortality in India. Recent studies estimate that 80,000 Indian children die each year due to measles and its complications, amounting to 4% of under-5 deaths. Immunization against measles directly contributes to the reduction of under five child mortality and hence to the achievement of Millennium Development Goal 4 (MDG 4). The l...

In 1999-2001, a national measles control strategy was implemented in Uganda, including routine immunization and mass vaccination campaigns for children aged 6 months to 5 years. This study assesses the impact of the campaigns on measles morbidity and mortality. Measles cases reported from 1992 through 2001 were obtained from the Health Management Information System, and measles admissions and d...

Introduction Measles is a vaccine preventable disease that has been successfully eliminated in some parts of the world. It causes high morbidity and mortality with the potential of large outbreaks. About a third of reported measles cases involve one or more complications including diarrhea, pneumonia, otitis media, blindness, post infections encephalitis and subacute sclerosing panencephalitis....

Measles remains a significant cause of childhood morbidity and mortality. Hallmark of the disease is a generalized immune suppression that can last for several weeks to months after resolution of measles virus (MV) infection [1–3], resulting in increased susceptibility to opportunistic infections [4–7]. At the same time, measles is associated with immune activation and induces strong MV-specifi...

Measles is one of the most contagious human diseases. Although mass vaccination programs have reduced the incidence of this disease, measles is still an important cause of morbidity and mortality among children in developing countries. Therefore the use of sensitive techniques to evaluate vaccine efficacy and level of immunity among members of susceptible communities is crucial. Serum neut...

has developed a global plan for accelerated measles control which calls for implementation of a strategy based on that used to successfully control measles in the Americas—a 'catch-up' campaign providing measles vaccine to all children (usually 9 months [or 1 year] to 14 years of age) regardless of prior history of immunization or disease, followed by high levels of routine coverage with measle...

Abstract Despite the availability of a safe and effective vaccine, measles still causes significant mortality morbidity among children in developing countries. As disease that induces immune amnesia with increased susceptibility to other infections but also life-long immunity measles, little is known about immunogenetics B cells elicit measles-specific antibodies (Abs) natural infection vs vacc...

Measles is the most transmissible infectious disease known n humans, and remains one of the top causes of death in chilren worldwide. Even in highly developed countries, measles ills approximately three of every 1000 persons infected. While o treatment exists for measles, prevention in the form of accination has been available since the 1960s. Despite the sigificant global morbidity and mortali...

BACKGROUND Measles is a highly contagious infectious disease with a significant public health impact especially among displaced populations due to their characteristic mass population displacement, high population density in camps and low measles vaccination coverage among children. While the fatality rate in stable populations is generally around 2%, evidence shows that it is usually high amon...