Microstructure and mechanical properties of non-equiatomic (CuNi)100−xCox (x=15, 20, 25 30, at.%) medium-entropy alloys (MEAs) prepared by vacuum arc-melting were investigated. Results show that all the as-cast MEAs exhibit dual face-centered cubic (fcc) solid-solution phases with identical lattice constant, showing typical dendrite structure consisting (Ni, Co)-rich phase in dendrites Cu-rich ...

Micro-Electrode Arrays (MEAs) have emerged as a mature technique to investigate brain (dys)functions in vivo and in in vitro animal models. Often referred to as "smart" Petri dishes, MEAs have demonstrated a great potential particularly for medium-throughput studies in vitro, both in academic and pharmaceutical industrial contexts. Enabling rapid comparison of ionic/pharmacological/genetic mani...

Let m, n ≥ 0, λ > 1, and R be a rational function with numerator, denominator of degree ≤ m,n, respectively. In several applications, one needs to know the size of the set S ⊂ [0, 1] such that for r ∈ S, max |z|=r |R (z)| / min |z|=r |R (z)| ≤ λ. In an earlier paper, we showed that meas (S) ≥ 1 4 exp ( − 13 log λ ) , where meas denotes linear Lebesgue measure. Here we obtain, for each λ, the sh...

The emerging field of neuroprosthetics is focused on design and implementation of neural prostheses to restore some of the lost neural functions. Remarkable progress has been reported at most bioelectronic levels—particularly the various brain-machine interfaces (BMIs)—but the electrode-tissue contacts (ETCs) remain one of the major obstacles. The success of these BMIs relies on electrodes whic...

Quantification of succulence should ideally convey information about physiological function and yet also be straightforward to measure. While important aspects of succulence and its physiological consequences may be quantified using parameters derived from pressure-volume (P-V) curves, this technique applied to succulent tissues is difficult, time consuming and generally not suitable for large ...

BACKGROUND To ensure rapid access to new potentially beneficial health technologies, obtain best value for money, and ensure affordability, healthcare payers are adopting a range of innovative reimbursement approaches that may be called Managed Entry Agreements (MEAs). METHODS The Health Technology Assessment International (HTAi) Policy Forum sought to identify why MEAs might be used, issues ...

Complementing single electrode recordings, passive, substrate-integrated thin-film microelectrode arrays (MEAs) have become established tools to investigate spatio-temporal patterns of electrical activity and neuronal interaction in-vitro. In the neurosciences, acute brain slices with accessible and well-preserved neuronal microcircuitry have become the most widespread preparation, that can als...

Because the Developmental Neurotoxicity Testing Guidelines require large numbers of animals and is expensive, development of in vitro approaches to screen chemicals for potential developmental neurotoxicity is a high priority. Many proposed approaches for screening are biochemical or morphological, and do not assess function of neuronal networks. In this study, microelectrode arrays (MEAs) were...

OBJECTIVES We aimed to validate a new flow convergence (FC) method that eliminated the need to locate the regurgitant orifice and that could be performed semiautomatedly. BACKGROUND Complex and time-consuming features of previously validated color Doppler methods for determining mitral regurgitant volume (MRV) have prevented their widespread clinical use. METHODS Thirty-nine different hemod...

Abstrak Penelitian tindakan kelas ini bertujuan mengetahui peningkatan kemampuan berpikir reflektif dan hasil belajar matematika dengan menggunakan Model-Eliciting Activities (MEAs). Subjek penelitian adalah mahasiswa yang mengikuti mata kuliah Geometri Transformasi. Data berupa RPP, foto, observasi, daftar nilai tes. Teknik pengambilan data dilakukan cara dokumentasi tes prestasi matematika. U...