Storicamente: rivista scientifica di storia, open access, supportata dal Dipartimento Storia Culture Civiltà dell'Università Bologna. contemporanea, moderna, medievale, antica, antropologia e geografia

Overexpression of the epithelial specific matrix metalloproteinase inatrilysin (MAT) has been correlated with enhanced tumorigenicity and tumor cell invasion using in vitro model systems. We have determined the effects of MAT expression on the development of mammary tumorigenesis using transgenic mice that express human MAT under the control of the mouse mammary tumor virus (MMTV)-long terminal...

Aims—To investigate whether anomalies of transforming growth factor â type II receptor (TGF-â RII) expression occur in the early stages of laryngeal carcinogenesis and to assess their importance in the development of laryngeal squamous cell carcinoma. TGF-â RII status was examined in laryngeal premalignant lesions coupled with malignant evolution and compared with a control group of similar les...

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Background: Given the importance of scattered and low doses in secondary cancer caused by radiation treatment, the point dose of critical organs, which were not subjected to radiation treatment in breast cancer radiotherapy, was measured.Objective: The purpose of this study is to evaluate the peripheral dose in two techniques of breast cancer radiotherapy with two energies. Methods: Eight diff...

ti,2f3= 99.0 ± 44.5 mm, t112y = 1213 ± 493 mm, V@ (Va) 4.81 ±2.l2lihens, V@= 58.2 ±50.Slihens,V7 = 598 ±294 liters. Vincnishine, studied only for hhe finsh 4 hn, behaved like a Iwo-compartment system, wihh values of t,,2 a 3.37 ±0.72 min,t,,2 /3 = 155 ±18 mm, v@= 4.53 ±0.49 liters, and V@ = 57.3 ± 21.1 liters. Urine excretiondaha demonstrahed that most drug elimination occurred wihhin ...