optimization of the exploitation operation is one of the most important issues facing the mining engineers. since several technical and economic parameters depend on the cut-off grade, optimization of this parameter is of particular importance. the aim of this optimization is to maximize the net present value (npv). since the objective function of this problem is non-linear, three methods can b...

Bronchiectasis is a multidimensional disease and, therefore, its severity or prognosis cannot be adequately quantified by analysing one single variable. The objective of the present study was to develop a multidimensional score that classifies the severity of bronchiectasis according to its prognosis. This is an observational multicentre study including 819 patients diagnosed with non-cystic fi...

One of the most difficult problems in mining operation is how to determine optimum cut-off grades of ores at different periods over the lifespan of the mine that will maximize the net present value (NPV) of the mine. Maximizing the NPV of a mining operation, subject to different constraints is a nonlinear programming problem. Cut-off grade optimization is used to arrive at an operating strategy...

abstract to evaluate the effects of the irrigation termination in different growth stages on yield and its components of autumn’s canola cultivars in isfahan region. an experiment was conducted in 2005-2006 in kabotar abad research station. a split plot layout within a randomized complete block design with tree replication was used. main plots were seven level of the irrigation cut-off time (d1...

Cut-off grade is one of the very important technical and economic parameters, which affects the economic and social efficiency in a mine enterprise. It is also the basis of the deposits technical economy evaluation, feasibility study, mining planning and design and the foundation of the decision-making in mining investment. Thereby, cut-off grade optimization is one of the core contents and the...

Lack of point-of-care tests for tuberculosis (TB) result in diagnostic delay, and increased mortality and healthcare-related costs. The urine Determine(TM) TB-LAM point-of-care strip-test was evaluated in 335 prospectively-recruited hospitalised patients with suspected TB-HIV co-infection (group 1) and from 88 HIV-infected hospitalised patients with non-TB diagnoses (group 2). Cut-off point-spe...

Background Radiolabeled prostate-specific membrane antigen (PSMA) has proven to be a highly accurate method to detect recurrence and metastases of prostate cancer, but only sparse data is available about its performance in the diagnosis of clinically significant primary prostate cancer. Methods We compared 68Ga-PSMA-11 PET/CT in 25 patients with 18FEC PET/CT in 40 patients with suspected pros...

BACKGROUND The skin is considered a critical organ at risk in carbon ion radiotherapy (CIRT) for locally advanced malignant bone and soft tissue tumors (MBSTs). The predictive factors for acute skin reactions after CIRT have not been investigated. The present study aimed to identify these factors and evaluate the correlation between the severity of acute skin reactions and skin dose parameters....

Optimization of the exploitation operation is one of the most important issues facing the mining engineers. Since several technical and economic parameters depend on the cut-off grade, optimization of this parameter is of particular importance. The aim of this optimization is to maximize the net present value (NPV). Since the objective function of this problem is non-linear, three methods can b...

PURPOSE To investigate dynamic contrast enhanced-MRI (DCE-MRI) in the preoperative chemo-radiotherapy (CRT) assessment for locally advanced rectal cancer (LARC) compared to18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT). METHODS 75 consecutive patients with LARC were enrolled in a prospective study. DCE-MRI analysis was performed measuring SIS: linear ...