BACKGROUND/AIMS Diabetes is well-known to influence endothelial function. Endothelial function and blood flow regulation might be different in diabetic and non-diabetic pregnancy. However, the impact of umbilical blood flow regulation in gestational diabetes on fetal development is unknown so far. METHODS In a prospective birth cohort study, we analyzed the association of the umbilical artery...

Background—Maternal diabetes mellitus in pregnancy results in greater offspring adiposity at birth. It is unclear whether it is associated with greater adiposity into adulthood, and if so, whether this is via intrauterine mechanisms or shared familial characteristics. Methods and Results—A record-linkage prospective cohort study of 280 866 singleton-born Swedish men from 248 293 families was us...

OBJECTIVE To assess the relationship between low maternal serum 25-hydroxyvitamin D levels and gestational diabetes mellitus in Turkish pregnant women according to the severity of 25-hydroxyvitamin D deficiency and assess intact parathyroid hormone levels in women with gestational diabetes mellitus and controls with low and sufficient 25-hydroxyvitamin D levels. METHODS We analyzed serum 25-h...

Recent studies show that higher blood glucose values after a 75 g oral glucose tolerance test in pregnancy are associated with higher rates of perinatal and maternal complications. Treatment of gestational diabetes mellitus (hyperglycaemia in pregnancy) reduces the risk of complications. Gestational diabetes mellitus is an asymptomatic condition. Screening is the only strategy for diagnosing th...

OBJECTIVES Environmental factors play an important role in the pathogenesis of type 1 diabetes mellitus, many of these factors have been uncovered despite much research. A case-control study was carried out to determine the potential maternal, neonatal and early childhood risk factors for type 1 diabetes mellitus in children and adolescents in Basrah. METHODS A total of 96 diabetic patients w...

objective: the high prevalence of gestational diabetes mellitus (gdm) in iran and its maternal and fetal consequences as well as the high risk of its long-term effects including obesity is known. the aim of this study was to evaluate the relationship between body mass index (bmi) in ages of 18 months and 6 years and maternal glucose concentration. materials and methods: this is a retrospective ...

Despite the dramatic decline in maternal and perinatal morbidity and mortality over the past few decades, controversy still exists regarding the care of pregnant women with both pregestational and gestational diabetes mellitus. Carbohydrate intolerance is the most common metabolic complication of pregnancy. A review of the literature over the last two decades indicates that the incidence of ges...

Gestational diabetes mellitus is defined as carbohydrate intolerance of variable severity with onset or first recognition during pregnancy. It has been shown that the risk of adverse maternal, foetal, and neonatal outcomes in gestational diabetes mellitus is related to the degree of glucose intolerance and/or hyperglycaemia; gestational diabetes mellitus also has long-term sequelae for both the...

Data from birth certificates in the United States indicate that maternal diabetes complicates 2%-3% of all pregnancies, but these data may underestimate the true prevalence of maternal diabetes in pregnancy. Two major forms of maternal diabetes may occur during pregnancy: preexisting or "pregestational" diabetes, and gestational-onset or gestational diabetes mellitus (GDM). Only the former is k...

Understanding the experiences of a pragmatic lifestyle intervention for women with gestational diabetes mellitus and overweight/obesity to reduce maternal weight at 12 months postpartum - Volume 82 Issue OCE4