German demographic or educational projections are conventionally based on macrosimulation or period microsimulation models. In this paper we introduce a discrete-event microsimulation model, which we have designed to project the graduate rates of the German population. In this model we use survival functions to calculate different fertility rates by mothers’ education. This paper describes how ...

Methods A Markov microsimulation model was developed to project lifetime health-related outcomes, costs, qualityadjusted life years (QALYs), and cost-effectiveness of ATV/r versus LPV/r, both with tenofovir-emtricitabine, as first-line ART. Virologic suppression, baseline characteristics, state transition probabilities, cholesterol changes, and adverse effects were based on 96-week CASTLE resul...

In this paper, some vital methodological issues of spatial microsimulation modelling for small area estimation have been addressed, with a particular emphasis given to the reweighting techniques. Most of the review articles in small area estimation have highlighted methodologies based on various statistical models and theories. However, spatial microsimulation modelling is emerging as a very us...

Different health economic (HE) models are used to simulate real-world practice. The choice of model depends on the disease arearesearch question, and objectives. In cancer screening tests, two common issues that risk changes dramatically over patient’s lifetime protocols usually a combination tests (eg, initial follow-up testing). There limitations properly addressing these in HE models. presen...

While static microsimulation models of the tax-transfer system are now available throughout the developed world, health microsimulation models are much rarer. This is, at least in part, due to the difficulties in creating adequate base micro-datasets upon which the microsimulation models can be constructed. In sharp contrast to tax-transfer modelling, no readily available microdata set typicall...

It is the growing societal interest about the individual and its behaviour in our and 'modern' societies which is asking for microanalyses about the individual situation. In order to allow these microanalyses on a quantitative and empirically based level microsimulation models were developed and increasingly used for economic and social policy impact analyses. Though microsimulation is known an...

More than 10 years ago O’Donoghue (2001) surveyed the dynamic microsimulation models that had been developed up to that point. However the 2000’s have seen many of the barriers that existed for model development up until that point overcome. This paper surveys the development and practices in dynamic microsimulation over the past decade, and discusses the methodological challenges today. The pa...

Available published research on microsimulation tends to focus on the results of policy simulations rather than upon validation of the models and their outputs. Dynamic population microsimulation models, which age an entire population through time for some decades, create particular validation challenges. This article outlines some of the issues that arise when attempting to validate dynamic po...