In many physical, technological, social, and economic applications, one is commonly faced with the task of estimating statistical properties, such as mean first passage times of a temporal continuous process, from empirical data (experimental observations). Typically, however, an accurate and reliable estimation of such properties directly from the data alone is not possible as the time series ...

1 Public Library of Science, Cambridge, United Kingdom, 2 National Cancer Institute, SAIC-Frederick, Maryland, United States of America, 3 Tel Aviv University, Tel Aviv, Israel, 4 Department of Pharmacology, University of California San Diego, La Jolla, California, United States of America, 5 Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, Ca...

An appreciation of the potential applications of molecular biology is of growing importance in many areas of life sciences, including marine biology. During the past two decades, the development of sophisticated molecular technologies and instruments for biomedical research has resulted in significant advances in the biological sciences. However, the value of molecular techniques for addressing...