Purpose: The aim of this study was to evaluate the effect of two gingival finishing lines (90° shoulder and deep chamfer) on the marginal fitness of two types of full anatomic all-ceramic crowns; zirconia crowns (Zikonzhan) and glass ceramic crowns (IPS e-max CAD) milled with CAD/CAM system. Materials and Methods: Two dentoform teeth of left maxillary first molar were prepared with chamfer fini...

Evolutionary biologists typically predict future evolutionary responses to natural selection by analysing evolution on an adaptive landscape. Much theory assumes symmetric fitness surfaces even though many stabilizing selection gradients deviate from symmetry. Here we revisit Lande's adaptive landscape and introduce novel analytical theory that includes asymmetric selection. Asymmetric selectio...

OBJECTIVE Muscular fitness levels have been associated with cardiometabolic risk in children, although whether body weight acts as a confounder or as an intermediate variable in this relationship remains controversial. The aim of this study was to examine whether the association between muscular fitness and cardiometabolic risk factors is mediated by body mass index (BMI). DESIGN AND METHODS ...

Analysis of the complete genome sequence of Saccharomyces cerevisiae confirms and extends earlier evidence that a majority of yeast genes are not essential, at least under laboratory conditions. Many fail to yield a discernible mutant phenotype even when disrupted. Genes not subject to natural selection would accumulate inactivating mutations, so these "cryptic" genes must have functions that a...

3-D reconstruction in Nuclear Medicine imaging using complete Monte-Carlo simulation of trajectories usually requires high computing power. We are currently developing a Parisian Evolution Strategy in order to reduce the computing cost of reconstruction without degrading the quality of results. Our approach derives from the Fly algorithm which proved successful on real-time stereo image sequenc...