Roy’s largest root is a common test in multivariate analysis of variance (MANOVA), with applications in several other problems, such as signal detection in noise. In this paper, assuming multivariate Gaussian observations, we derive a simple yet accurate approximation for the distribution of Roy’s largest root test, in the extreme case of concentrated non-centrality, where the signal or differe...

Progressive resistance training has positive effects on the health of elderly people, however exercise programs for seniors frequently focus on other forms of exercise. This study is a randomised trial with a blinded assessor comparing a community based progressive resistance training program (n = 20) with a flexibility program (n = 20), both one hour twice weekly for 10 weeks. Outcomes were st...

This paper considers testing the equality of multiple high-dimensional mean vectors under dependency. We propose a test that is based on a linear transformation of the data by the precision matrix which incorporates the dependence structure of the variables. The limiting null distribution of the test statistic is derived and is shown to be the extreme value distribution of type I. The convergen...

The objective of this work was to study, among breast cancer patients, if Internet health information use is associated with coping. Questionnaires were completed (n = 178) regarding Internet use and also coping as measured by the Brief Cope. MANOVA analyses were conducted for the 14 coping subscales. Following a significant MANOVA omnibus test, univariate ANOVA and multivariate ANCOVA analyses...

MOTIVATION Oligonucleotide arrays such as Affymetrix GeneChips use multiple probes, or a probe set, to measure the abundance of mRNA of every gene of interest. Some analysis methods attempt to summarize the multiple observations into one single score before conducting further analysis such as detecting differentially expressed genes (DEG), clustering and classification. However, there is a risk...