Cissampelos pareira Linn. (Menispermaceae) widely distributed all over India and it is widely used for various kidney disorders. According to the Ayurveda, the kidneys are made up of the "Rakta" and "Meda" dhatus. Treating these two dhatus is also an effective way to treat the kidneys. The plant Cissampelos pareira Linn. is used to treat these two dhatus. This promotes us to undertake a study t...

BACKGROUND Natural honey (honey) is considered as a part of traditional medicine all over the world. It has both antimicrobial and antioxidant properties, useful in stimulation of wounds and burns healing and gastric ulcers treatment. The aim of this study, for the first time, was to investigate the antioxidant properties and protective role of honey against carcinogen chemical aflatoxin (AF) e...

BACKGROUND Homonoia riparia is a plant, which is widely used in the indigenous system of medicine for the treatment of urolithiasis, renal disorders and inflammatory conditions. This is the first report on the antioxidant and nephroprotective activities of whole plant of H. riparia. OBJECTIVE The present study aims at investigating the in vitro antioxidant and nephroprotective activity of the...

Renal disorders have become very common nowadays, which may also lead to kidney failure. The disorder may be caused by the commonly used chemicals such as acetaminophen, CCl4, streptromycin, H2O2 etc. The objective of this work is to determine the nephroprotective potential of ethanolic extract against H2O2 induced toxicity in VERO cell line. Ethanolic extract is known for its antioxidant, anti...

This study investigated the nephroprotective effect of curcumin against acetaminophen (APAP)induced nephrotoxicity in rats. APAP-induced nephrotoxicity was evident by a significant increase (P<0.01) of urea and creatinine in serum. Furthermore, a significant increase (P<0.01) of lipid peroxidation as malondialdehyde (MDA), nitric oxide (NO), protein carbonyl (PC) contents, interleukin-1β(IL-1β)...

Hippocratea africana root used locally in the treatment of poisoning was investigated to confirm its antidotal potential rats. The extract (200-600 mg/kg) and fractions; dichloromethane (DCM) aqueous, 400 were evaluated for nephroprotective activity against doxorubicin-induced kidney injury Kidney function parameters, oxidative stress markers histology assess protective effect extract. fraction...

OBJECTIVES To evaluate the effect of Graptophyllum pictum on lipid peroxidation and tissue antioxidant enzymes in liver and kidney of gentamicin induced nephrotoxic rats. MATERIALS AND METHODS Animals were grouped into 6: Group 1 received gum acacia, Group 2 received G. pictum ethanol extract (300 mg/kg), Group 3 received gentamicin, Groups 4, 5, 6 received gentamicin along with G. pictum at ...

Introduction: Nephropathy is one of the progressive complications prevailed all around the world that is observed which arises due to detrimental effects of metabolites created due to various metabolic and physiological reactions. Gentamicin is one of the drug that may cause nephrotoxicity. Objectives: Phytoremedies are being considered as to play deterrent role in the treatment of disease. T. ...

the   stembark of mammea africana is used traditionally for the treatment of stomach pains. the present study was designed to evaluate the effects of ethanolic stembark extract of mammea africana on experimentally induced diarrhoea and ulcer . the extract ( 30 – 90mg/kg) was administered orally in rats 30 minutes to one hour before the induction of diarrhoeal and ulcer using different experimen...

OBJECTIVE The purpose of the present study was to evaluate the nephroprotective and antioxidant properties of Triphala against bromobenzene-induced nephrotoxicity in female Wistar albino rats. METHODS Animals were divided into five groups of six rats and treated as follows: Group I was a normal control and received no treatment, Group II received only bromobenzene (10 mmol/kg), Groups III and...