An effective technological approach to produce adaptogenic microingredients is concentrate plant biologically active substances via sorption on various matrices. The aim was develop and evaluate in vivo the phytoecdysteroids flavonoids extracted from quinoa grain sorbed coagulated chicken egg protein. consecutive extraction of conducted followed by experiment performed during 37 days using Wist...

The involvement of free radicals in the carcinogenic mechanism has been suggested, however, little is known about the role of free radicals in the pancreatic cancer. In this study, the effects of active oxygen on the carcinogenesis of the tumor were examined by measuring the levels of scavengers in pancreatic cancer of Syrian golden hamsters. Pancreatic cancer was induced by di-iso-propanol nit...

The acid treatment of a ruthenabenzene yielded an unusual dialdehyde. Interestingly, this dialdehyde has notable anti-oxidative properties and resists even nitric acid. This stability is confirmed by chemical and electrochemical experiments. In addition, a stable cyclic anhydride is synthesized from the dialdehyde via an environmentally friendly electrochemical method.

Dynamic proteoids are dynamic covalent analogues of proteins, which can be used as new adaptive biomaterials. We designed and synthesized a range of sugar-containing dynamic proteoid biodynamers based on the polycondensation of different types of amino acid and dipeptide hydrazides with a biological aliphatic dialdehyde and a nonbiological aromatic dialdehyde. By using the saccharide-based dial...

The NADPH-dependent respiratory burst oxidase of human neutrophils catalyzes the reduction of oxygen to superoxide using NADPH as the electron donor and is essential for normal host defenses. To gain insight into the function of the various oxidase subunits that are required for the full expression of catalytic activity, we studied the interactions between the 2',3'-dialdehyde derivative of NAD...

BACKGROUND Approximately 20% of women in Germany are smokers, and some of them are unable to stop smoking during pregnancy. As cigarette smoke generates free radicals, it has been suggested that it may be one of the major sources of oxidant stress in pregnant women and unborn fetuses. On the other hand, the human placenta is known to be a major source of pro-oxidant agents, antioxidant enzyme s...

Cypermethrin (αCyano-3-Phenoxybenzyl (+ cis, trans) 3-(2, 2-Dichlorovinyl)-2, 2-dimethyl cyclopropane carboxylate) is an active pyrethroid which intensively controls a wide range of pests in agriculture and an ecto-parasiticide in humans and animals. It has moderate carcinogenic, mutagenic, immunosuppressive and hepatotoxic effects. It causes brain and locomotor disorders, polyneuropathy. The p...