most serious problem that leads to reproductive system failure in both human and animals. Present study was carried out to investigate whether hydroalcholic extract of Dorema aucheri leaves could protect the male rats against lead-induced reproductive toxicity. Materials and Methods: Adult wistar rats were treated with 0.1% lead acetate in drinking water with or without 100, 200 and 400 mg/kg D...

Endosulfan is an organochlorine insecticide and acaracide used to control a broad range of insect and arthropod pests on a wide variety of crops in many agrosystems. It can cause acute and chronic toxicity. Endosulfan is a neurotoxin, haematoxin, genotoxin and nephrotoxin. Toxicity of this insecticide on reproductive organs is confirmed. So this article reviews experimental and epidemiological ...

Background: Recent evidence has indicated a deterioration in reproductive health of men in many countries over the past few decades, particularly a decrease in semen quality and an increase in prevalence of prostate cancer. The human male has a relatively low fertility potential as compared to other mammals. Thus, the human male may be at greater risk from reproductive toxicants. For example, t...

Diesel exhaust particles (DEPs) are particulate matter from diesel exhaust that contain many toxic compounds, such as polyaromatic hydrocarbons (PAHs). Some toxicities of PAH are thought to be expressed via aryl hydrocarbon receptors (AhRs). The male reproductive toxicity of DEPs might depend on AhR activation induced by PAHs. We hypothesized that AhR antagonists protect against the male reprod...

cyclophosphamide (cp) is extensively used as an antineoplastic agent for treatment of various cancers, as well as an immunosuppressive agent. however, despite its wide spectrum of clinical uses, cp is known to cause several adverse effects including reproductive toxicity in humans and experimental animals. crataegus monogyna is one of the oldest medicinal plant has been shown to be cytoprotecti...

This study investigated the toxicity of sodium fluoride on male reproductive hormones and ameliorative effects extract Phyllantus amarus adult albino rats. The consisted six equal groups five rats that were administered with over a period two weeks. result indicates possible hormone lipid profile probable capacity to ameliorate this toxicity.