A new type of maize mitochondrial genome has been identified in the male fertile (normal) inbred line A188. It has been named NA (N in the A188 nuclear background). In comparison to previously described maize mitochondrial genomes, it is classified as a new type since the genome contains unique DNA sequences and unique sets of repeated sequences, and has a unique organization. This brings the n...

To shed light on various causes of reproductive failure by unravelling the male gamete genome using whole exome sequencing (WES). In a 5-year period, 18 consenting couples, with normal semen parameters, negative female infertility workups, and failed ART cycles, comprised infertile cohort. Ten matched successful outcomes, served as fertile control. DNA was extracted amplified from at least 500 ...

Remarkable advancement in next generation sequencing technology has made personal genome analysis feasible and affordable. Here we present the whole sequence of an individual from Kashmir region India who is pandit community (IHGP04). The Indian male’s was sequenced at 38.6 X coverage with a total 110 Gb data generated using Illumina HiSeq 2000 platform. variant revealed over 3.6 million single...

Abstract Background Cytoplasmic male sterility (CMS) is a trait associated with non-functional pollen or anthers, caused by the interaction between mitochondrial and nuclear genes. Findings A Tadukan-type CMS line (TAA) restorer (TAR) were obtained successive backcrossing Oryza sativa cultivars Tadukan (a cytoplasmic donor) Taichung 65 recurrent parent). Using Illumina HiSeq, we determined whol...

Selfish genetic elements (SGEs) increase their transmission efficiency relative to the rest of individual genome, which is often deleterious fitness. Theoretical studies have suggested that intragenomic conflict over sex ratio distortion between SGEs and genome should lead evolution sex-determining systems. However, in insects, there are relatively few other than those on Dipterans, makes it di...

Izumo1 is a testis-specific gene product, whose function is essential for sperm-egg fusion. Throughout its lifespan, Izumo1 is posttranslationally modified, being both N-linked glycosylated on its extracellular domain and phosphorylated on the intracellular C-terminal tail. Within the caput regions of the rat epididymis, two phosphorylation events have been documented. However, as sperm pass th...

growing amount of information on biological sequences has made application of statistical approaches necessary for modeling and estimation of their functions. in this paper, sensitivity and specificity of the first and second markov chains for prediction of genes was evaluated using the complete double stranded  dna virus. there were two approaches for prediction of each markov model parameter,...