SMA-DMSO complex (RISUG) is a potent anti fertility compound developed by Prof.S.K Guha at IITKharagpur.It has been fabricated as a male contraceptive which works by lowering the pH of vas deference in males and hence damaging the sperms.Cytotoxicity of SMA-DMSO was assessed using COMET assay whereby concentration of SMA-DMSO ranging from .001 M to 1 M was tested for inducing any significant ...

The male contraceptive agent gossypol was found to induce a dose related increase of DNA strand breaks in human fibroblasts in vitro at concentrations of 5 to 40 micrograms/ml. The effect was reduced in the presence of 2% fetal calf serum. A weak but reproducible increase in the SCE frequency was found in human lymphocytes treated for 1 hour in serum-free medium with 0.04 to 4 micrograms/ml of ...

The GnRH analogue deslorelin, as a subcutaneous implant, was initially developed in Australia as an ovulation-inducing agent in mares. Its uses, for the suppression of reproduction in the domestic dog and cat and in other species, including humans, have been developed subsequently. Such implants have been used as a contraceptive modality in a variety of wild carnivores, both males and females. ...

Current male hormonal contraceptive (MHC) regimens act at various levels within the hypothalamic pituitary testicular axis, principally to induce the withdrawal of the pituitary gonadotrophins and in turn intratesticular androgen production and spermatogenesis. Azoospermia or severe oligozoospermia result from the inhibition of spermatogonial maturation and sperm release (spermiation). All regi...

Family planning programs are considered to be an important way to control the rapid population growth of Bangladesh with the main focus being women. As a male dominant country, the knowledge of, attitude towards, and approval of family planning is largely influenced by the male member of couples in their choice of appropriate contraceptive methods. This paper examined the determinants of curren...

This article interrogates the modes by which cultural constructions of male contraceptive use emerge in Costa Rica by analyzing men's narratives of vasectomy. Drawing on ethnographic research data, I examine men's contraceptive decision making and perspectives on vasectomy and specify the ways they work through their vasectomy to rearticulate the relationship between masculinity and contracepti...