Objective(s):This study was designed to investigate the effect of Phaleria macrocarpa aqueous extract (PM) on spermatogenesis by observing the histological changes of testes in adult male rats. Materials and Methods: PM was prepared by boiling the dried slices of P. macrocarpa fruits followed by filtering, centrifugation and freeze-drying to obtain the powder form. Eighteen Sprague Dawley adult...

A short-term deprivation of rat pups from breastfeeding in the early postnatal period leads to MS at age 4-6 months. However, this neonatal model requires optimization and a detailed study into metabolic hormonal parameters adult animals. The aim work was these male rats deprived breast milk 19-21 days, which achieved by treating lactating females with bromocriptine. Adult showed an increased b...

Background Biorotox® is an invented green biologic rodenticide. The present study was designed to determine whether this toxin could cause infertility in male rats. MaterialsAndMethods Sixteen Sprague-Dawley adult male rats were randomly divided into control and treatment groups. Treatment group was received diets containing Biorotox ® for 35 days. Control group was given standard rat food. Wei...

In agreement with previous results (Awapara, 1956), we noted that the taurine level in the liver of the adult female rat is higher than in the adult male rat: 9.44 and 2.08, respectively, expressed as a concentration (mumoles/g of liver). Furthermore, we observed a significant decrease of the taurine level (expressed similarly) in the liver of the lactating rat: 1.84 twenty-one days after the b...

background: arsenic toxicity is a major global health problem and exposure via contaminated drinking water has been associated with hematological and other systemic disorders. the present investigation has been conducted in adult male rats to evaluate the protective ability of α-lipoic acid (ala) against such hematological disorders. methods: twenty-four adult male wister rats (b.wt.130±10g) we...

Rat pups become immobile and analgesic when exposed to an adult male rat. The aim of this study was to determine whether these reactions are under the control of endogenous opioids and to determine the role of the midbrain periaqueductal gray (PAG), which mediates stress-induced immobility and analgesia in adult animals. In Experiment 1, 14-day-old rats were injected systemically with the gener...

results results showed that dex 1 significantly increased, while dex 30 and groups treated with zinc 10 mg/kg and zinc 20 mg/kg decreased total immobility time as compared to that of saline group. also there was a significant decrease of total immobility time when zinc administered to rats already received dex 1, compared with that of control group. conclusions the current study findings sugges...