Transcription activator-like effectors (TALEs) are secreted by plant-pathogenic Xanthomonas bacteria into plant cells where they act as transcriptional activators and, hence, are major drivers in reprogramming the plant for the benefit of the pathogen. TALEs possess a highly repetitive DNA-binding domain of typically 34 amino acid (AA) tandem repeats, where AA 12 and 13, termed repeat variable ...

Plant-pathogenic Xanthomonas bacteria inject transcription activator-like effector proteins (TALEs) into host cells to specifically induce transcription of plant genes and enhance susceptibility. Although the DNA-binding mode is well-understood it is still ambiguous how TALEs initiate transcription and whether additional promoter elements are needed to support this. To systematically dissect pr...

Once upon a time in faraway places, stories were told around campfires and hearths among family and friends. Eventually these oral stories were written down and some were illustrated. Two of the best-known names in written folk literature are the Frenchman Charles Perrault and the Grimm Brothers of Germany. In 1697 Perrault published a collection entitled Tales of Mother Goose, and from 1812 to...

Recombinant transcription activator-like effectors (TALEs) have been effectively used for genome editing and gene regulation applications. Due to their remarkable modularity, TALEs can be tailored to specifically target almost any user-defined DNA sequences. Here, we introduce fairyTALE, a liquid phase high-throughput TALE synthesis platform capable of producing TALE-nucleases, activators, and ...

We describe the settings of a project that aims at giving a robot the ability to tell tales to children. The choices made to produce the linguistic and behavioral expressivity required to produce a credible storytelling are detailed.

the aim of this study is to investigate the role and the place of women and men in vulgar tales in the 60 selected vulgar tales exploiting parsons’ role theory and the infra- analysis method.the case tales are among which are narrated by people older than 50 years old. this paper aims, first to review the cultural elements which are verbally transferred from generation to generation, and, secon...

This chapter describes a study that investigates the potential value of using traditional fairy tales as reading material for English language learners (ELL). Using the computational textual analysis software, the Gramulator, the authors analyzed the linguistic features of fairy tales relative to a corpus of ELL reading material and a corpus of baseline educational texts for native English spea...