نتایج جستجو برای: lytic phage

تعداد نتایج: 28621  

Journal: :iranian journal of veterinary research 2014
a. k. mishra n. sharma a. kumar n. kumar m. r. gundallahalli bayyappa

in the present study, the therapeutic potential of bacteriophages virulent to staphylococcus aureus associated with goat mastitis were isolated, identified and assessed. staphylococcus aureus (host or indicator bacterium) was isolated from a goat suffering from clinical mastitis. based on cultural, morphological, biochemical tests and amplification of s. aureus specific thermonuclease gene inpc...

Journal: :Viruses 2019

2016
Luis A. Estrella Javier Quinones Matthew Henry Ryan M. Hannah Robert K. Pope Theron Hamilton Nimfa Teneza-mora Eric Hall Biswas Biswajit

Skin and soft tissue infections (SSTI) caused by methicillin resistant Staphylococcus aureus (MRSA) are difficult to treat. Bacteriophage (phage) represent a potential alternate treatment for antibiotic resistant bacterial infections. In this study, 7 novel phage with broad lytic activity for S. aureus were isolated and identified. Screening of a diverse collection of 170 clinical isolates by e...

2017
Kinga I. Stanczak-Mrozek Ken G. Laing Jodi A. Lindsay

Objectives Horizontal gene transfer of antimicrobial resistance (AMR) genes between clinical isolates via transduction is poorly understood. MRSA are opportunistic pathogens resistant to all classes of antimicrobial agents but currently no strains are fully drug resistant. AMR gene transfer between Staphylococcus aureus isolates is predominantly due to generalized transduction via endogenous ba...

Journal: :Journal of bacteriology 2007
Simon J Labrie Sylvain Moineau

In this study, we demonstrated the remarkable genome plasticity of lytic lactococcal phages that allows them to rapidly adapt to the dynamic dairy environment. The lytic double-stranded DNA phage ul36 was used to sequentially infect a wild-type strain of Lactococcus lactis and two isogenic derivatives with genes encoding two phage resistance mechanisms, AbiK and AbiT. Four phage mutants resista...

Journal: :The Journal of General Physiology 2003
A. P. Krueger N. S. West

Dilute solutions of MnCl(2) or MnSO(4) accelerate the lytic effect of phage upon susceptible staphylococci. Under the conditions of our experiments the manganese-containing mixtures lysed regularly 0.5 hour sooner than the controls. The effect is shown to be due to a lowering of the lytic threshold, i.e. the quantity of phage/bacterium requisite for lysis; Mn(++) reduces the ratio from 54 to ab...

Journal: :Archives of Virology 2021

This work describes the characterization and genome annotation of newly isolated lytic phage vB_SsoM_Z31 (referred to as Z31), from wastewater samples collected in Dalian, China. Transmission electron microscopy revealed that Z31 belongs family Myoviridae, order Caudovirales. specifically infects Shigella sonnei, dysenteriae, Escherichia coli. The is an 89,355-bp-long dsDNA molecule with a G+C ...

Journal: :jundishapur journal of microbiology 0
muhammad hidayat rasool department of microbiology, government college university, faisalabad, pakistan; department of microbiology, government college university, faisalabad, pakistan. tel: +92-419201205; +92-3017102378 rukhsana yousaf department of microbiology, government college university, faisalabad, pakistan abu baker siddique department of microbiology, government college university, faisalabad, pakistan muhammad saqalein department of microbiology, government college university, faisalabad, pakistan mohsin khurshid college of allied health professionals, directorate of medical sciences, government college university, faisalabad, pakistan

conclusions the overall results indicated that bacteriophages isolated from sewage exhibited excellent lytic activity against mrsa strains. in conclusion, bacteriophages can be further characterized and appear to be a promising candidate for phage therapy against mrsa in the future. results the phages exhibited good lytic activity against mrsa when tested in-vitro, and the highest activity was ...

2013
Hema Gopalaiah

Bacteriophages are the viruses with either DNA or RNA as the genetic material.1 Phages have a developmental cycle within the host bacteria which can be lytic or lysogenic. The lytic cycle comprises has a series of events that subsequenty release daughter phage particles. Phage for a given bacterium can be isolated wherever that bacterium grows.2 The problem is not just isolating the phage again...

2013
Lorena Rodríguez-Rubio Beatriz Martínez Ana Rodríguez David M. Donovan Friedrich Götz Pilar García

The increase in antibiotic resistance world-wide revitalized the interest in the use of phage lysins to combat pathogenic bacteria. In this work, we analyzed the specific cleavage sites on the staphylococcal peptidoglycan produced by three phage lytic proteins. The investigated cell wall lytic enzymes were the endolysin LysH5 derived from the S. aureus bacteriophage vB_SauS-phi-IPLA88 (phi-IPLA...

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