www.pharmtech.com yophilization or freeze-drying is often used to stabilize various pharmaceutical products, including virus vaccines, protein and peptide formulations, liposome, and small-chemical drug formulations (1–4). Often a pharmaceutical product may be susceptible to physical and chemical degradation when stored as a ready-to-use solution. The goal of the formulations scientist is to id...

The maintenance of viable and stable Xanthomonas cells is crucial for the xanthan reliable research industrial production. method, storage recovery conditions should preserve both viability phenotypical genotypical features. Here, effectiveness classical methods on long-term preservation different arboricola pathovar pruni strains was to determine. Strains were preserved by monthly sub-culturin...

Background & Aims: Amniotic membrane persists for a long time after ocular transplantation (as corneal substitute) and can affect light transmission (transparency). The aim of this study was to evaluate the transparency of amniotic membrane after freeze-drying (lyophilization) and to compare the results with transparency of rabbit cornea. Methods: Transparency of rabbits’ corneas and fresh and ...

The preservation of Brucella melitensis was of initerest because Elberg and Faunce (1957) had shown that a nondependent mutant derived from a streptomycindepenident strain of B. melitensis was immunogeniic wheni administered as a living vaccine. Huttoni et al. (1951) and, more recenitly, Alexander and van Drimmelen (1956), showed that lyophilization was practical for preserving the viability of...

The stability (longevity of activity) three crude urease extracts was evaluated in a laboratory study as part an effort to reduce the cost for applications that do not require high purity enzyme. A low-cost, stable source will greatly facilitate engineering such biocementation soil. Inexpensive have been shown be effective at hydrolyzing urea carbonate precipitation. However, some studies sugge...

In recent years, photosynthetic microalgae regained attention for biodiesel production. For efficient utilization of microalgae, a number of criteria including a strain with high biomass and lipid productivities and employment of effective and reliable methods for oil extraction from the obtained biomass should be met. Recently, we have isolated and identified three thermo-resistant green micro...

Since the pioneer work of Rogers (1914) on drying cultures from the frozen state and the wide application of this procedure to bacteria, the lyophil process has been shown to be a successful method for the preservation of yeast cultures in a viable state over extended periods (Elser et al., 1935; Wickerham and Andreasen, 1942; Wickerham and Flickinger, 1946). The fundamental value of this metho...