نتایج جستجو برای: lymphoblastic
تعداد نتایج: 35386 فیلتر نتایج به سال:
purpose: to report an unusual ocular presentation of a relapse of acute lymphoblastic leukemia. case report: a 9-year-old girl presented with a subconjunctival mass and ipsilateral preauricular lymphadenopathy. she had history of acute lymphoblastic leukemia (all) in remission but had a normal blood cell profile. because of corneal dellen formation and enlargement of the mass over a 2-week peri...
T-cell acute lymphoblastic leukemia is an aggressive hematologic malignancy which is usuallyassociated with unfavorable prognosis particularly in patients with refractory/relapsed disease.Therefore, development of novel therapeutic strategies is highly required for improving theoutcome of these patients. Although there are several studies evaluating the efficacy of proteasome<...
Sgc8c aptamers on a stiff polymer scaffold form multivalent inhibitor targeting acute lymphoblastic leukemia.
Aim: Leukemia targets are one of the most common childhood malignancies. Epstein-Barr virus is a tumorigenic virus of the herpes family of viruses and causes primary infection in young children. The aim of this study was to evaluate the increase in NFKB expression following EBV virus and its contribution to the half-life of EBV-positive acute lymphoblastic leukemia patients. Materials and Meth...
FACTORS EFFECTIVE IN THE PROGNOSIS OF NEUTROPENIC FEVER CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA
hypercalcemia complicating malignancy is a rare complication in pediatric age group. in this article, we present a case with acute lymphoblastic leukemia presenting as severe hypercalcemia. a 10 years old girl presented with an acute onset of fever, nausea, vomiting, loss of weight, costovertebral pain and frequency. she was admitted with a presumptive diagnosis of acute pyelonephritis. her exa...
T-cell acute lymphoblastic leukemia arises from the leukemic transformation of developing thymocytes and results from cooperative genetic lesions. Inactivation of the PHF6 gene is frequently observed in T-cell acute lymphoblastic leukemia, suggesting an important tumor suppressive role for PHF6 in the pathobiology of this leukemia. Although the precise function of PHF6 is still unknown, this ge...
acute leukemia which is the most common cancer in children is a heterogeneous group of clonal malignancies. the conversion of the leukemic cell lineage during the course of the disease or later is termed lineage switch. it has been rarely reported in the literature. in leukemia lineage switch, conversions from lymphoblastic leukemia to myeloid leukemia or vice versa are reported. herein, we rep...
acute lymphoblastic leukemia (all) is one of the most common cancers among children. although there have been tremendous treatments, none of them have led to a precise cure. the use of herbal medicines which are safe and non-toxic have been demonstrated in this study. curcumin is a polyphenol, hydrophobic product that is derived from turmeric plant. curcumin has anti-toxic, anti-bacterial, anti...
nucleostemin (ns), a stem cell-abundant nucleolar protein, is critical for maintaining the self-renewal and proliferative properties of normal and cancerous stem cells. recent data suggests that ns signaling is important for proliferation of t-cells and leukemia cells. this study was conducted to verify the role of ns in pathogenesis and treatment of t-cell acute lymphocytic leukemia (t-all). o...
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