نتایج جستجو برای: lvad
تعداد نتایج: 1550 فیلتر نتایج به سال:
RESULTS Overall, AF was documented in 80 patients (32%) following LVAD placement. Before LVAD placement, 182 patients had no history of AF, whereas 67 patients had documented AF. Among these 67 patients, 56 (84%) continued to have AF following LVAD placement; 24 patients without a history of AF (13%) developed AF after LVAD placement. Patients manifesting AF after LVAD placement were more likel...
BACKGROUND AND PURPOSE Stroke is a major adverse event after left ventricular assist device (LVAD) surgery. The purpose of this study was to describe differences in hemispheric distribution of stroke in LVAD patients. METHODS We reviewed 317 consecutive patients who underwent LVAD surgery between November 2000 and July 2011. Stroke during LVAD support was analyzed. RESULTS In total, 46 stro...
BACKGROUND There are few data describing the longitudinal use of and adherence to heart failure medications following left ventricular assist device (LVAD) implantation. METHODS AND RESULTS Using a large US commercial insurance database, patients who received an LVAD (International Classification of Diseases, 9th Revision, Clinical Modification code 37.66) and survived to hospital discharge w...
BACKGROUND Unloading a failing heart with a left ventricular assist device (LVAD) can improve ejection fraction (EF) and LV size; however, recovery with LVAD explantation is rare. We hypothesized that evaluation of myocyte contractility and biochemistry at the sarcomere level before and after LVAD may explain organ-level changes. METHODS AND RESULTS Paired LV tissue samples were frozen from 8...
Background Unloading a failing heart with a left ventricular assist device (LVAD) can improve ejection fraction (EF) and left ventricular (LV) size; however, recovery with LVAD explantation is rare. We hypothesized that evaluation of myocyte contractility and biochemistry at the sarcomere level before and after LVAD may explain organ level changes. Methods and Results Paired LV tissue samples w...
Quality of Life and Influential Factors in Patients Implanted With a Left Ventricular Assist Device.
BACKGROUND Improving quality of life (QOL) has become an important goal in left ventricular assist device (LVAD) therapy. We aimed (1) to assess the effect of an implantable LVAD on patients' QOL, (2) to compare LVAD patients' QOL to that of patients in different stages of heart failure (HF), and (3) to identify factors associated with patients' QOL. METHODSANDRESULTS The QOL of 33 Japanese i...
BACKGROUND Heart failure patients have inadequate nutritional intake and alterations in metabolism contributing to an overall energy depleted state. Left ventricular assist device (LVAD) support is a common and successful intervention in patients with end-stage heart failure. LVAD support leads to alterations in cardiac output, functional status, neurohormonal activity and transcriptional profi...
OBJECTIVE It is suggested that apoptosis plays a role in heart diseases. The effect of left ventricular assist device (LVAD) on apoptosis at ischemia-reperfusion myocardial injury is unclear. We investigated the effect by assisting the ischemia-reperfusion myocardial injury models with LVAD. METHODS Twelve swines were divided into two groups: the control group and LVAD group. The diagonal bra...
Background—Technological advancements of left ventricular assist devices (LVAD) have created today’s potential for extending the lives of patients with end-stage heart failure. Few studies have examined the effect of LVAD therapy on patient-reported outcomes (PROs), such as health status, quality of life, and anxiety/depression, despite poor PROs predicting mortality and rehospitalization in pa...
BACKGROUND Inflammation is a critical process contributing to heart failure (HF). We hypothesized that IL-33/ST2 pathway, a new mechanism regulated during cardiac stress, may be involved in the functional worsening of end-stage HF patients, candidates for left ventricular assist device (LVAD) implantation, and potentially responsible for their outcome. METHODS IL-33, ST2, and conventional cyt...
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