conclusions chronic smoking caused left ventricular diastolic dysfunction. acute intake caused left and right ventricular diastolic dysfunction. changes persisted up to 30 minutes after smoking, although diastolic blood pressure returned to normal state. objectives the current study aimed to evaluate the acute and chronic effects of smoking on the left and right ventricular (rv) diastolic funct...

Left ventricular (LV) diastolic filling is abnormal at rest in many patients with coronary artery disease (CAD), even in the presence of normal resting LV systolic function. To determine the effects of improved myocardial perfusion on impaired. LV diastolic filling, we studied 25 patients with one-vessel CAD by high-temporal-resolution radionuclide angiography before and after percutaneous tran...

Comprehensive and precise assessment of left ventricular (LV) systolic and diastolic function is necessary to establish, or exclude, heart failure as a cause or component of dyspnea. Echocardiography with Doppler readily assesses LV diastolic function; advantages include that echocardiography is non-invasive, does not require radiation, is portable, rapid, readily available, and in competent ha...

BACKGROUND Diastolic heart failure often coexists with atrial fibrillation (AF). Elevated plasma levels of natriuretic peptides are the left ventricular (LV) marker of diastolic dysfunction. AIM To evaluate the influence of sinus rhythm restoration on ANP and BNP levels in patients with normal and impaired LV diastolic function. METHODS The study included 42 patients (19 men, 23 women), age...

BACKGROUND In congenital aortic stenosis, chronic pressure load has detrimental effects on left ventricular (LV) systolic and diastolic function. Reduction in LV pressure load with balloon aortic valvuloplasty (BAVP) may improve diastolic function. METHODS AND RESULTS Echocardiographic and catheterization data for 25 consecutive patients undergoing BAVP for congenital aortic stenosis were ret...

PURPOSE To assess the impact of left ventricular (LV) diastolic dysfunction on left atrial (LA) phasic volume and function using dual-source CT (DSCT) and to find a viable alternative prognostic parameter of CT for LV diastolic dysfunction through quantitative evaluation of LA phasic volume and function in patients with LV diastolic dysfunction. MATERIALS AND METHODS Seventy-seven patients we...

OBJECTIVE The relationship of mitral annular (MA) kinetics to left ventricular (LV) and left atrial (LA) function before and after mitral valve (MV) repair has not been well studied. Here we sought to provide comprehensive analysis that relates to MA motions, and LA and LV diastolic function post MV repair. METHODS Three-dimensional analyses of mitral annular motion, LA function, and LV volum...

BACKGROUND Although left ventricular (LV) diastolic dysfunction is associated with increased risk for incident heart failure in patients with coronary artery disease (CAD), no specific treatment for diastolic abnormalities has been established. Animal and small human studies have shown that an acute increase in LV afterload adversely impacts on LV early diastolic relaxation, but little is known...

We used a load-insensitive index of systolic left ventricular (LV) function and an analysis of diastolic pressure-dimension relationships to test the hypothesis that recombinant human (rh) tumor necrosis factor-alpha (TNF alpha) impairs LV function in dogs. Animals were studied 7-10 d after aseptic implantation of instrumentation to monitor cardiac output, external anterior-posterior LV diamete...

To characterize the acute effects of nifedipine on left ventricular (LV) systolic and diastolic function, we studied 32 patients stratified with respect to baseline LV function before and 30 minutes after nifedipine (20 mg sublingually) with a randomized, single-blind protocol. Nineteen patients received nifedipine and 13 received placebo. No change occurred in any variable after placebo. Nifed...