Background: Increasing number of patients facing end-organ failure, as well as the therapeutic challenges surrounding allotransplantation, has catalyzed the evolution of tissue engineering and regenerative medicine. The successful recapitulation of development requires choosing an ideal scaffold material as a mediator of biochemical and biophysical signals. The extracellular matrix (ECM) functi...

Introduction: Physical activity of any intensity and time effect on the oxidative stress and Antioxidant system. So, the proper choice of type, time and intensity of exercise is necessary. Therefore, the aim of the present study was to investigate the effect of 8 weeks of strenuous endurance (SET) and high intensity interval training (HIIT) on the TRX1 and MDA of lung tissue in male wistar rats...

Abstract Background: Inhalation of Sulfur mustard (HD) will cause lung epithelial inflammation and injury. There are different results from the prophylactic effects of amifostine (AM) on protection of lung epithelial tissue against HD. The aim of this study was to evaluate the prophylactic effects of AM on protection of rat lung tissue exposed to HD. Methods: In this study twenty Albino Wis...

Background: The aim of this study was to investigate the Evaluation of Changes in Gene Expression of TGF-β, MMP-2 and TIMP-1 in Lung Tissue of male wistar rats Following 6 Weeks of High Intensity Interval and Endurance Training. Method: In this experimental study, 18 male wistar rats (6 to 8 months) were selected and randomly divided into three groups of control (Con), moderate intensity conti...

 Connective tissue diseases, including scleroderma, may be associated with an increased risk of lung cancer. The most common type of lung cancer associated with systemic sclerosis is adenocarcinoma or bronchoalveolar carcinoma, and small cell carcinoma is rare. This reports presents a 54-year-old non-smoker woman with a history of scleroderma who was examined due to aggravation of shortness of ...