Introduction: Rheumatoid arthritis (RA) is the most common autoimmune disease, leading to the destruction of the joints and causing pain, disability, and immobility in the patients. Radiosynovectomy (RSV) has been applied as an effective treatment for the patients with resistant synovitis after failure of long-term pharmacotherapy and intra-articular steroid injection for more than 50 years. Se...

The M1 muscarine agonist, 5-(2-ethyl-2H-tetrazol-5-yl)-1-methyl-1,2, 3,6-tetrahydropyridine (Lu 25-109), is extensively metabolized in mice, rats, dogs, and humans. The metabolite profile after an oral dose of [(14)C]Lu 25-109 was determined in plasma and in urine. Lu 25-109 was metabolized by N-demethylation (Lu 25-077), N-oxidation (Lu 32-181), and N-deethylation (Lu 31-126). In addition, com...

Introduction: In Peptide Receptor Radionuclide Therapy (PRRT), the administration of radionuclide such as Lu-177 label with a pharmaceutical agent useful to destroy the lesion. The amount of Lu-177 radioactivity administered to the patients is still not standardize and generally not more than 7.4 GBq per session due to the patient’s safety issues. The first cycle of Lu-177 is a...

Abstract This chapter considers the LU factorization of a general nonsymmetric nonsingular sparse matrix A . In practice, numerical pivoting for stability and/or ordering to limit fill-in in factors is often needed and computed then permuted PAQ Pivoting discussed Chapter 7 algorithms 8

The Lutheran (Lu) blood group antigens and the B-cell adhebut includes several potential binding sites for the ubiquitous Sp1 transcription factor. In addition, the distal 5* region, sion molecule (B-CAM) epithelial cancer antigen are carried by recently cloned integral glycoproteins that belong to the encompassing nucleotidesÏ673 toÏ764, contains clustered binding sequences for the GATA, CACCC...

— We study the microlocal analyticity of solutions u of the nonlinear equation ut = f(x, t, u, ux) where f(x, t, ζ0, ζ) is complex-valued, real analytic in all its arguments and holomorphic in (ζ0, ζ). We show that if the function u is a C2 solution, σ ∈ CharLu and 1 i σ([Lu, Lu]) < 0 or if u is a C3 solution, σ ∈ CharLu, σ([Lu, Lu]) = 0, and σ([Lu, [Lu, Lu]]) 6= 0, then σ / ∈WFau. Here WFau de...