Dermonecrotic toxin (DNT), lipopolysaccharide (LPS), and lymphocytosis-promoting factor (LPF) were isolated from Bordetella pertussis and tested for neuroactivity. When injected intraperitoneally into rats, a dose of 0.13 mg of LPF per kg elevated the cyclic GMP level in cerebellum by approximately 70%, whereas DNT (0.5 mg/kg) and LPS (1.5 mg/kg) were without effect. This action of LPF on the c...

The purified lymphocytosis promoting factor (LPF) from Bordetella pertussis was found to be a potent mitogen for peripheral blood lymphocytes (PBL) from normal adults as well as for cord blood lymphocytes. Proliferation occurred in autologous plasma or fetal calf serum, regardless of previous exposure to pertussis infection or immunization. Only one adult human serum, from a physician constantl...

Complexity reduction is an important task in Bayesian networks. Recently, an approach known as the linear potential function (LPF) model has been proposed for approximating Bayesian computations. The LPF model can effectively compress a conditional probability table into a linear function. This correspondence extends the LPF model to approximate propagation in Bayesian networks. The extension f...

Leukocytosis-promoting factor (LPF) was purified from the supernatant of a 5-day liquid culture of Bordetella pertussis strains Tohama and no. 134. The preparations appeared to be filamentous molecules (2 by 40 nm) and contained histamine-sensitizing and hemagglutinin activities in addition to leukocytosis-promoting activity. Active protection tests in mice demonstrated strong protective activi...

Biosafety Level 3 (BL-3) laboratories are designed to prevent the escape of pathogenic microorganisms by operating at negative pressure so that if microorganisms become airborne, they remain within the laboratory. However, the authors are not aware of any published evidence or international guidance on the level of pressure differential required for BL-3 laboratories. This uncertainty was refle...

The low pass filter (LPF) algorithm, which is used to calculate the average queue length in the random early detection (RED) algorithm, results in a poor response time when RED recovers from congestion. In this paper, we propose a new algorithm, called low pass filter/over drop avoidance (LPF/ODA), to improve the response time of RED. LPF/ODA is based on reducing the time required by RED to rec...

OBJECTIVE To investigate the multifactorial relationship between illness insight, cognitive and emotional processes, and illness characteristics in bipolar disorder patients. METHODS Data from 85 euthymic or mildly to moderately depressed bipolar disorder patients were evaluated. Insight was measured using the Mood Disorder Insight Scale (total score and subscale scores: awareness of illness,...

Infection with Shiga toxin-producing Escherichia coli (STEC) O157:H7 is characterized by acute inflammation of the colonic mucosa. STEC O157:H7 contains two non-identical loci encoding long polar fimbriae (Lpf), which play a role in the STEC colonization of the intestinal epithelial cells. However, no information is available regarding the involvement of Lpf in the STEC-induced host inflammator...

It is well known that partial functions arise frequently in formal reasoning about programs. A partial function may not yield a value for every member of its domain. Terms that apply partial functions thus may not denote, and coping with such terms is problematic in two-valued classical logic. A question is raised: how can reasoning about logical formulae that can contain references to terms th...

We present efficient algorithms for storing past segments of a text. They are computed using two previously computed read-only arrays (SUF and LCP) composing the Suffix Array of the text. They compute the maximal length of the previous factor (subword) occurring at each position of the text in a table called LPF. This notion is central both in many conservative text compression techniques and i...