Objective: To determine lipid derangements in HIV-positive patients receiving anti-retroviral therapy (ART).
 Study Design: Comparative cross-sectional study.
 Place and Duration of study: Chemical Pathology Department, cooperation with the Department Virology at Armed Forces Institute (AFIP), Rawalpindi Pakistan, from Mar 2019 to 2020.
 Methodology: In this study, two groups wer...

Introduction Elevated serum triglycerides, total cholesterol, very lowdensity lipoprotein (VLDL) cholesterol, and low-density lipoprotein (LDL) cholesterol have been reported in the literature from areas where experience with antiretroviral drugs has amassed. Up until recently the use of antiretroviral drugs in Nigeria on a wide scale was a rarity owing largely to prohibitive cost, and so exper...

Objective: This study aimed to explore the relation between bone mineral density (BMD), inflammation, coronary risk factors, and Insulin growth factor (IGF) in frail elderly. Design: A casecontrol study. Setting: Ain Shams University Hospital Cairo, Egypt. Participants: Ninety aged 60 years and above; sixty frail (30 males and 30 females; mean age 70.03 ± 8.10) and thirty matched controls (15 m...

OBJECTIVE To compare the Friedewald and modified Friedewald formulae with direct homogeneous assay for serum lowdensity lipoprotein cholesterol (LDL-C) levels estimation. STUDY DESIGN Cross-sectional study. PLACE AND DURATION OF STUDY Armed Forces Institute of Pathology, Rawalpindi, from June to December 2011. METHODOLOGY Healthy subjects of either gender, from Rawalpindi, aged 18-75 year...

1. Seven patients with type I1 hyperlipoproteinaemia were treated with the bile acid-sequestering resin, colestipol (5 g three times daily), after a prolonged period of taking placebo. 2. After 8-9 weeks of treatment, the plasma concentration of the non-esterified cholesterol of very-low-density lipoprotein (VLDL) had risen by a mean of 0.09 mmol/l(43% increase, P<O-OOl), that of the esterified...

Blood viscosity is a crucial hemodynamic biomarker because it determines the friction against blood vessels, the quantity of oxygen that is delivered to organs and tissues, and the degree of exertion by the heart. Many factors affect blood viscosity, either directly or inversely. e.g., fibrinogen and hematocrit. The effect of other factors (e.g., cholesterol) on blood viscosity is still under i...

The updated clinical guidelines for cholesterol testing and management (Adult Treatment Panel (ATP) IV) from the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults are under development and due to be published in 2012. These influential guidelines are organized and funded by the National Heart, Lung, and Blood Institute (NHLBI) and carry the imprimatur of t...

Vol. 35 No. 4 • April 2010 • P&T® 197 INTRODUCTION Hyperlipidemia is extremely prevalent in both men and women today. Total cholesterol (TC) levels, as well as lowdensity lipoprotein-cholesterol (LDL-C) levels, usually increase throughout our lives. Nearly half of all Americans older than 20 years of age have TC levels exceeding 200 mg/dL. Only 50% of adults who qualify for lipid-lowering thera...

OBJECTIVE To assess the effects of exercise intervention on aerobic capacity, functional ability and lipid profile in patients after stroke with prior coronary artery disease. PATIENTS Fifteen patients after stroke with prior coronary artery disease. METHODS Patients were enrolled in a moderate-intensity exercise intervention using a graded treadmill for 12 weeks. Before and after the inter...

Alpinia zerumbet is a miao folk medicinal plant widely used in the Guizhou Province of southwest China that contains several bioactive constituents and possesses protective effects against cardiovascular diseases. In the present study, we evaluated the protective effect of essential oils derived from Fructus Alpiniae zerumbet (EOFAZ) on oxidized lowdensity-lipoprotein- (ox-LDL-) induced apoptos...