The paper presents the first known longitudinal study of the relationship between loneliness, depressive symptoms, and suicide ideation in adolescence, in a stratified sample of high school students (Time 1 N = 1009; 57 % female; Time 2 N = 541; 60 % female). Cross-lagged structural equation modeling indicated that depressive symptoms led to more loneliness across time, whereas loneliness did n...

BACKGROUND Adolescents' sleep duration and subjective psychological well-being are related. However, few studies have examined the relationship between sleep duration and subjective psychological well-being longitudinally across adolescence - a time of profound biological and psychosocial change. The aim of this longitudinal study was to investigate whether shorter sleep duration in adolescents...

Background: The effectiveness of treatment for people with substance use disorders is usually examined using longitudinal cohorts. In these studies, treatment is often considered as a time-varying exposure. The aim of this commentary is to examine confounding in this context, when the confounding variable is time-invariant and when it is time-varying. Method: Types of confounding are described ...

BACKGROUND Past research has shown links between both children's aggressive behaviour and a lack of prosocial behaviour to later maladaptation. Both types of behaviours have also been identified as crucial in children's social and emotional development and later (mal)adaptation. However, little is known about the way they predict each other over time. METHODS We utilised a large, ethnically d...

Associations between cannabis use and psychotic outcomes are consistently reported, but establishing causality from observational designs can be problematic. We review the evidence from longitudinal studies that have examined this relationship and discuss the epidemiologic evidence for and against interpreting the findings as causal. We also review the evidence identifying groups at particularl...

Hippocampal place responses can be prospectively or retrospectively modulated by the animal's future or prior trajectory. Two main hypotheses explain this. The "multiple-map hypothesis" switches between different maps for different trajectories (rate remapping). In contrast, in the "buffer hypothesis," the hippocampus encodes an ongoing representation that includes the recent past and/or the im...

BACKGROUND The level of frailty in the older population across age cohorts and how this changes is a factor in determining future care costs and may also influence the extent of socioeconomic and gender inequalities in frailty. METHODS We model cohort-specific trajectories in frailty among the community dwelling population older than 50 years, using five waves (2002-2010) of the English Longi...

Variable and person-oriented analyses were used to explore the associations between personality and three previously untested general iris characteristics: crypts, pigment dots and contraction furrows. Personality data, as measured by the NEO PI-R and ratings of iris characteristics from 428 undergraduate students were collected. Crypts were significantly associated with five approach-related b...

conclusions alterations in consumption of whole grains, vegetables, and added sugars are associated with body weight change, suggesting that it could be helpful in weight control. results in men, weight loss was significantly predicted only by decreased intake of added sugars (or: 2.21, 95% ci: 1.06-4.63). in women, weight gain was significantly predicted by decreased intake of whole grains (or...