نتایج جستجو برای: local relapse
تعداد نتایج: 564483 فیلتر نتایج به سال:
BACKGROUND In the medical literature many analyses of outcomes of sarcoma patients were performed without regard to the problem of "competing risks." METHODS We analyzed local relapse-free and metastasis-free survival in a population of 3255 adult patients with a primary soft-tissue sarcoma (STS) included in the French Sarcoma Group database. Cumulative incidence of local and metastatic relap...
Recurrence of prostate cancer is suspected when an increase in the prostate-specific antigen level is detected after radical treatment; the recurrence could be local relapse, distant relapse, or both. Differentiation between the two patterns of relapse is critical for choosing the proper treatment strategy. Choline PET/CT could be of help in discriminating patients with local, lymph node, and b...
INTRODUCTION Breast conserving surgery combined with sentinel node biopsy represents currently the gold standard of treatment for early breast cancer. Although breast conserving surgery has been a widely accepted method for many years, there remain some highly controversial unresolved issues. The present analysis focused on the resection margin as one of the key factors for local control of the...
BACKGROUND The AMORE protocol is a local treatment for patients with nonorbital pediatric head and neck rhabdomyosarcoma (HNRMS). The objectives of this study were: (1) to assess the adequacy of the concept, and (2) to identify factors associated with relapse. METHODS We performed a retrospective multidisciplinary review of 22 children primarily treated according to the AMORE protocol, exclud...
BACKGROUND Outcome data in young women with ductal carcinoma in situ (DCIS) are rare. The benefits of boost radiotherapy in this group are also unknown. We aimed to assess the effect of boost radiotherapy in young patients with DCIS. METHODS We included 373 women from 18 institutions who met the following inclusion criteria: having tumour status Tis and nodal status (N)0, age 45 years or youn...
Background & Aims: It is more than half of a century that the drug of choice for treatment of cutaneous leishmaniosis (CL) has been pentavalent antimony compounds such as meglumine antimoniate (Glucantime). The aim of the present study was to evaluate the efficacy, relapse and treatment failure of intralesional Glucantime plus cryotherapy in the treatment of anthroponotic CL (ACL). Methods: The...
BACKGROUND There are no consistent agreements on whether radiotherapy after breast-conserving surgery (BCS) could provide local control and survival benefit for older patients with early breast cancer or breast ductal carcinoma in situ (DCIS). The present study aimed to evaluate the efficacy of radiotherapy after BCS in older patients with early breast cancer or DCIS. RESULTS Radiotherapy cou...
PURPOSE The past two decades has seen significant improvement in the overall survival of patients with favorable histology Wilms tumor (FHWT); however, this progress has reached a plateau. Further improvements may rely on the ability to better stratify patients by risk of relapse. This study determines the feasibility and potential clinical utility of classifiers of relapse based on global gene...
OBJECTIVES: The purpose of this analysis is to elucidate a relationship between cyclooxygenase-2 (COX-2) expression and local relapse in a large cohort of patients with T12N0 larynx cancer treated with primary radiation therapy. STUDY DESIGN: Please see Methods. METHODS: Clinical and molecular analyses were conducted on 123 patients with biopsy-proven T1-2N0 larynx cancer. Clinical prognostic f...
Approximately 10% to 15% of patients with stage I/II invasive breast cancer will develop a clinically isolated local recurrence. The standard management of an ipsilateral breast tumor recurrence following breast-conserving surgery and radiation is salvage mastectomy, while local excision and radiation are optimal treatment of a chest wall recurrence following initial mastectomy. Although there ...
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