Background: Cardiac complications due to iron overload are the most common cause of death in patients with thalassemia major. The aim of this study was to compare iron chelation effects of deferoxamine, deferasirox, and combination of deferoxamine and deferiprone on cardiac and liver iron load measured by T2* MRI. Methods: In this study, 108 patients with thalassemia major aged over 10 years...

background: a solitary necrotic nodule (snn) of the liver is an uncommon lesion, which is different from primary and metastatic liver cancers. objectives: to analyze the classification, ct and mr manifestation, and the pathological basis of solitary necrotic nodule of the liver (snn) in order to evaluate ct and mri as a diagnosing tool. patients and methods: this study included 29 patients with...

conclusion due to the significant improvement in the treatment of early stage of hcc compared to the previous decade, we suggest a fast, non-invasive, more accurate, but more expensive method (haste, op/ip t1w sequences mri combined with dwi) rather than us for the screening of hcc in liver cirrhosis. results combination of limited sequences mri and dwi had the highest accuracy (94.79%) followe...

Liver diseases can be diagnosed through various medical imaging schemes such as CT scans, ultrasounds, and MRIs [2]. Dynamic contrast- enhanced MRI provides the most comprehensive information for differential diagnosis of liver tumors [3].

Abstract Background Iron overload is the main transfusion related side effects in patients with transfusion dependent hemoglobinopathies. Severe iron deposition in tissues leads to organ dysfunction. Many organs can be affected such as heart, liver, and endocrine organs. Cardiac failure and liver fibrosis are the consequent of Iron overload in transfusion dependent hemoglobinopathy. Magne...

background hepatic fibrosis is a typical complication of chronic liver diseases resulting in cirrhosis that remains a major public health problem worldwide. liver biopsy is currently the gold standard for diagnosing and staging hepatic fibrosis. percutaneous liver biopsy; however, is an invasive procedure with risks of complications. therefore, there is need for alternative non-invasive techniq...

Abstract Background The purpose of this study was to investigate the diagnostic performance diffusion weight imaging (DWI), apparent coefficient (ADC) map, normalized ADC liver, and spleen compared dynamic contrast-enhanced MRI (DCE-MRI) in evaluation residual hepatocellular carcinoma (HCC) after radiofrequency ablation (RFA) using 3 T (T) magnetic resonance (MRI). Results A prospective perform...

Advances in the management of transfusion dependent thalassemic patients have improved the survival of these patients. The most important consequence of repeated and frequent transfusions is iron accumulation in vital organs. The magnetic resonance imaging (MRI) is a non-invasive and valid technique for the estimation of iron stores. Despite multiple studies about cardiac and liver MRI T2*, the...

Introduction: The liver fibrosis is caused by extracellular accumulation of cluster, glycos amino glycans and proteoglycans, which this extracellular accumulation may limit the penetration and molecular movement of water in the tissue, so the Diffusion weighted imaging(DWI) technique is due to the sensitivity to the movement and release of water molecules Can show this restrict...