Whilst archaeological evidence for many aspects of life in ancient China is well studied, there has been much less interest in ancient infectious diseases, such as intestinal parasites in past Chinese populations. Here, we bring together evidence from mummies, ancient latrines, and pelvic soil from burials, dating from the Neolithic Period to the Qing Dynasty, in order to better understand the ...

Liver fluke or Fasciola hepatica is a common parasite of livestock. A liver fluke infection causes ill health, as well as a reduction in growth rates and reproductive performance in affected livestock. Over recent years it has been acknowledged that the presence of liver fluke in the UK has increased and that the periods of risk for infections have become longer, as well as more difficult to pr...

Biliary liver flukes are common parasites in some regions of the world where consumption of raw fresh-water fish is a cultural practice. Clonorchis sinensis and Opisthorchis species are the major biliary liver flukes associated with human disease. Some of these parasites are highly associated with cholan...

Liver fl uke infection caused by Opisthorchis viverrini, O. felineus, and Clonorchis sinensis is a major public health problem in East Asia and Eastern Europe. Currently, more than 600 million people are at risk of infection with these trematodes [1]. O. viverrini is endemic in Southeast Asian countries, including Thailand, Lao People’s Democratic Republic, Vietnam, and Cambodia [2], and C. sin...

BACKGROUND Liver fluke infection of livestock causes economic losses of over US$ 3 billion worldwide per annum. The disease is increasing in livestock worldwide and is a re-emerging human disease. There are currently no commercial vaccines, and only one drug with significant efficacy against adult worms and juveniles. A liver fluke vaccine is deemed essential as short-lived chemotherapy, which ...

The stimulatory effect of serotonin on glucose uptake and lactic acid production in the parasitic trematode, the liver fluke, Fusciola hepatica, was reported previously (1). Subsequently, it was found that incubation of the intact liver fluke with serotonin results in an increase of glycolysis in cell:free homogenates (2). Evidence was presented indicating that this effect was partly due to an ...

BACKGROUND European liver fluke Opisthorchis felineus, causing opisthorchiasis disease, is widespread in Russia, Ukraine, Kazakhstan and sporadically detected in the EU countries. O. felineus infection leads to hepatobiliary pathological changes, cholangitis, fibrosis and, in severe cases, malignant transformation of bile ducts. Due to absence of specific symptoms, the infection is frequently n...

UNLABELLED Liver fluke Parafasciolopsis fasciolaemorpha is a parasite typical of elk (Alces alces). The present study describes the identification of a massive invasion of the liver fluke P. fasciolaemorpha in an elk in the Sobibór Landscape Park, Eastern Poland. In February 2016, samples of liver and faeces were collected from the elk during postmorte examination. A section of liver tissue and...

Trematodes are almost all hermaphrodite (schistosomes being the exception) flat worms (flukes) which have a two or more host life cycle, with snails featuring consistently as an intermediate host. Dogs and cats residing in Europe, including the UK and Ireland, are far less likely to acquire trematode or fluke infections, which means that veterinary surgeons are likely to be unconfident when the...

Human liver fluke infection caused by Clonorchis sinensis, Opisthorchis viverrini, and O. felineus remains a major public health problem, affecting the poor in the poorest regions of Asia. An estimated 45 million people are infected and more than 600 million are at risk of these infections [1,2]. This Viewpoint highlights the distribution of the infection, clinical features, neglect of liver fl...