background liver transplantation (lt) is the only treatment option for patients with advanced liver disease. currently, liver donation to these patients, considering priorities, is based on the model for end-stage liver disease (meld). meld score is a tool for predicting the risk of mortality in patients with advanced liver disease. however, few studies have so far been conducted in iran on the...

protein calorie malnutrition (pcm) is associated with an increased risk of morbidity and mortality in patients with cirrhosis and occurs in 50%-90% of these patients. although the pathogenesis of pcm is multifactorial, alterations in protein metabolism play an important role. this article is based on a selective literature review of protein and sodium recommendations. daily protein and sodium r...

conclusions our results suggest that liver cirrhosis does not cause impaired thrombopoietin production even in the late stage of disease. thrombopoietin has no contribution for the occurrence of thrombocytopenia in cirrhosis; splenic sequestration seems to be the main factor. results platelet counts were lower in patients with cirrhosis (97000 ± 8000/mm3) than in healthy subjects (240000 ± 5100...

results the allele and genotype distributions of pnpla3 rs738409 and rs2281135 were not significantly different between the chb and lc groups. after segregation on the basis of sex, no significant correlation between pnpla3 (rs738409 and rs2281135) genotypes/alleles and liver cirrhosis was detected. moreover, none of the haplotypes in pnpla3 (rs738409 and rs2281135) was found to be statisticall...

pulmonary aspergillosis is a well known entity occurring in immunocompetent persons. cutaneous aspergillosis, on the other hand, has been described in cases of suppressed immunity. recently, invasive aspergillosis has been reported in patients with subtle immune dysfunction such as those with critical illness and advanced cirrhosis. we report a case of scrotal aspergillosis in association with ...

Background: Intrapulmonary vascular abnormalities associated with liver cirrhosis may result in intrapulmonary right-to-left shunt and hypoxemia. The aim of this study was to use contrast enhanced echocardiography to detect intrapulmonary vascular abnormalities in patients with liver cirrhosis candidates for liver transplantation. Methods: One hundred and two adult patients underwent contrast e...

conclusions use of ha in an algorithm model, is an extra and valuable tool for assessing liver necro inflammatory injuries- in parallel with liver biopsy- but more comprehensive studies are needed to approve the use of ha as an appropriate clinical tool. results there are several scientific studies indicating ha as a biomarker for high score fibrosis and cirrhosis in various liver diseases alon...

a three-fold decrease of the in vitro ability of serum proteins to bind naproxen was shown in patients with cirrhosis of the liver compared to healthy individuals. this decrease was caused by quantitative changes in serum proteins in the sera of patients with liver damage. lower doses of naproxen are therefore suggested in the treatment of patients with liver dysfunction.