The three-dimensional collagen framework of human liver parenchyma in surgical specimens from patients with chronic active hepatitis (CAH), viral or alcoholic cirrhoses (LC) was observed by scanning electron microscopy after cell-maceration by the method of Ohtani (1988). In control livers, the tubular sheaths of collagen fibers housing the sinusoid were shown to form a labyrinthine network, wh...

BACKGROUND Population based mortality rates from liver cirrhosis, and alcohol consumption, have increased sharply in Britain in the past 35 years. Little is known about the long term trends over time in mortality rates after hospital admission for liver cirrhosis. AIMS To analyse time trends in mortality in the year after admission for liver cirrhosis from 1968 to 1999. SUBJECTS A total of ...

In Japan, several thousand people, three-quarters of whom were war-wounded, have been administered Thorotrast. An epidemiological follow-up study on Thorotrast-administered war-wounded veterans was initiated in 1963. The 7th survey of the study was conducted on 286 veterans at the end of 1986, of whom 262 had received Thorotrast intravascularly and 24 by other routes. Of those who had received ...

Background: Population based mortality rates from liver cirrhosis, and alcohol consumption, have increased sharply in Britain in the past 35 years. Little is known about the long term trends over time in mortality rates after hospital admission for liver cirrhosis. Aims: To analyse time trends in mortality in the year after admission for liver cirrhosis from 1968 to 1999. Subjects: A total of 8...

  Objectives and Background: Mutation directed inactivation of the tumor suppressor gene p53 have been found incountries with high frequency for hepatocellular carcinomas (HCCs). Our goal in the present study was screening of the p53 gene in tumor tissues from HCC affected individuals in southwest Iran for putative mutations in exons 7 and 8 that are known as hot spot regions. Materials & Met...

This study reports the incidence of HBsAg in a series of chronic lymphoproliferative disorders in which a high incidence of cirrhoses had been previously observed. Twenty-three cases were collected from the necropsy records. The type of lymphoma was reviewed in the light of the new functional classifications of non-Hodgkin malignant lymphomas introduced by Lennert and Lukes. The presence of HBs...