Title of Document: TUBULAR PERFUSION SYSTEM BIOREACTOR FOR THE DYNAMIC CULTURE OF HUMAN MESENCHYMAL STEM CELLS Andrew Bryan Yeatts, Doctor of Philosophy, 2012 Directed By: Associate Professor John P. Fisher, Fischell Department of Bioengineering In vitro culture techniques must be improved in order to increase the feasibility of cell based tissue engineering strategies. Limitations of current t...

since treatment of landfill leachate is quite complicated, there is a need to develop a system thatis capable of providing high treatment efficiencies. in this study, the treatment performance of a jet - loopmembrane bioreactor (jlmb) operated at different organic loading rates was investigated by observing thechanges in chemical oxygen demand (cod), total kjehldahl nitrogen (tkn) and total amm...

Alternative to the use of fossil fuels are biofuels (e.g., bioethanol, biodiesel and biogas), which more environmentally friendly can be produced from different renewable resources. In this investigation, bioethanol production raw sugar beet cossettes (semi-solid substrate) by yeast Saccharomyces cerevisiae in a horizontal rotating tubular bioreactor (HRTB) was studied. Obtained results show th...

a dissolved methane sensor based on silicone tube was designed, constructed and optimized.the silicone tube diameter, silicone tube length and helium flow rate (as the carrier gas(were considered as process parameters to be optimized.a continuous stream of helium (50 ml/min) was directed through the tubing, sweeping out the dissolved methane which diffused through the walls of the tubing from t...

lilium ledebourii (baker) boiss. (liliaceae) is a critically endangered lily species native tonorthern iran, where it is protected by law. in order to develop a cost effective method for largescalepropagation, the effects of three culture systems (solid, liquid and temporary immersion)and two types of cytokinins [6-benzyladenine (ba) and thidiazuron (tdz)] were studied onthe in vitro plant rege...

An adapted bioactive foamed emulsion bioreactor for the treatment of benzene vapor has been developed. In this reactor, bed clogging was resolved by bioactive foam as a substitute of packing bed for interfacial contact of liquid to gaseous phase. The pollutant solubility has been increased using biocompatible organic phase in liquid phase and this reactor can be applied for higher inlet benzene...

In this paper an observability analysis is performed for an axial dispersion tubular bioreactor that involves one nonlinear growth reaction. The process is described by a semilinear parabolic Partial Differential Equation (PDE). More precisely, the analysis is performed on a tangent linearized model, that is described by a linear PDE with a spatial-dependent coefficient. It is reported that the...

Cell Culture Bioreactors Basic Types of Bioreactors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1 Stirred Tank (Well Mixed) vs. Tubular Reactor (Plug Flow) . . . . . . . . . . . . . . . . . 3 Segregated Bioreactors (Dead Zone Present) Compartmentalized Bioreactors . . 4 Implication When Growth or Reaction Occurs in the Reactor . . . . . ....

In recent years, there has been a growing interest in bioreactors, which utilise immobilised enzymes and cells in order to improve the bioprocess productivity. In fact, there are many specific advantages of the immobilised systems in comparison with the more conventional systems, in which the bio-agents are suspended freely (cells) or dissolved in a bulk aqueous medium (enzymes): • high cell de...

The development of energy-efficient solutions for large-scale fermenters demands a deep and comprehensive understanding hydrodynamic heat mass transfer processes. Despite wide variety research dedicated to measurements intensity in bubble flows, this subject faces new challenges due the topical innovative bioreactor designs. In order understand fluid dynamics gas–liquid medium, researchers need...