Retinoblastoma Y79 cells exposed to a hematoporphyrin derivative and light were examined with regard to the production of intracellular lipid peroxide and morphologic changes, in the presence or absence of oxygen. The intracellular lipid peroxide was related to the dose of hematoporphyrin derivative and the duration of photoradiation, under aerobic conditions. The formation of lipid peroxide wa...

A sequential injection analysis (SIA) system with spectrophotometric detection was developed as an alternative method for estimating the concentration of lipid hydroperoxides, which are the primary products of the lipid peroxidation process. The lipid hydroperoxide quantification was based on a ferric thiocyanate method. Benzoyl peroxide was used to produce a standard calibration curve for the ...

Endometrial bleeding problems can be the major reason for discontinuing progestin-only contraception. In this study the endometrial angiogenic response in Norplant users was found to be lower than in women with normal menstrual cycles. These disturbances in angiogenic response may be caused by oxidant-antioxidant imbalance in the endometrium. The aims of this study were to investigate the effec...

Gingival response to periodontal inflammation generates excessive lipid peroxide and such a condition may augment systemic health through increased circulating lipid peroxide. The purpose of the present study was to investigate whether the generation of lipid peroxide in periodontal inflammation could induce tissue injury in the liver, heart, kidney and brain using a rat model. Twelve Wistar ra...

I. The micro-iodimetric method has been used to study some factors affecting the concentration of lipid peroxides in the adipose tissue of vitamin E-deficient rats. 2. Cod-liver oil methyl esters (CLOME) or maize oil methyl esters (MOME) with peroxide values ranging from 3 to 330p-equiv.lg were given by mouth to vitamin E-deficient rats deprived of food before and after the dose. Lipid peroxide...

We hypothesized that AA-2414, a novel thromboxane receptor blocker with antioxidant properties, would inhibit peroxide-induced vasoconstriction in the isolated perfused human placental cotyledon. In study 1, placental cotyledons (n = 5) were perfused serially for 20- min intervals with control KrebsRinger-bicarbonate (KRB) buffer, t-butyl hydroperoxide (Px; 100 microM), KRB buffer, and KRB buff...

Skin is one of the main targets for reactive oxygen species; thus, reactive oxygen species-induced damage and protein and lipid modifications occur, and skin can undergo a wide array of diseases, from photosensitivity to cancer. In this study, human dermal fibroblasts exposed to hydrogen peroxide (0-1000 micromol/L) exhibited a marked increase in both protein carbonyls and 4-hydroxy-2-nonenal, ...

abstract this experiment was carried out to determine the effects of proline and ascorbic acid on chilling injury, electrolyte leakage, lipid peroxidation, peroxide hydrogen and antioxidant enzymes activity of thompson grape (vitis vinifera l.) fruit. grape fruits were treated by 0 (control), 250 and 500 µm proline and 0 (control), 2 and 4% ascorbic acid and their combinations, then stored at 1...