A ltered concentrations of blood plasma lipoproteins are powerful predictors of coronary heart disease (CHD) and of other manifestations of atherosclerosis. Reduction of elevated low-density lipoprotein cholesterol (LDL cholesterol) and concomitant increases in high-density lipoprotein cholesterol (HDL cholesterol) have been shown to reduce myocardial infarction and death from CHD in people wit...