Breast cancer is already the most common malignancy affecting women worldwide, and evidence is mounting that breast cancer induced by circadian disruption (CD) is a warranted concern. Numerous studies have investigated various aspects of the circadian clock in relation to breast cancer, and evidence from these studies indicates that melatonin and the core clock genes can play a crucial role in ...

The heritable component of breast cancer accounts for only a small proportion of total incidences. Environmental and lifestyle factors are therefore considered to among the major influencing components increasing breast cancer risk. Endocrine-disrupting chemicals (EDCs) are ubiquitous in the environment. The estrogenic property of EDCs has thus shown many associations between ongoing exposures ...

Energy efficiency has become a major research topic in the Internet community as a result of unprecedented rise in the Information and Communication Technology (ICT) sector. One typical approach towards energy efficiency is to select a subset of IP routers or interfaces that will go to sleep mode during the off-peak period. However, on-the-fly network reconfiguration is generally deemed harmful...

Loss of epithelial cell polarity and inflammation are hallmarks of breast cancer development. Although the association between the disruption of tissue polarity and inflammation has been demonstrated, we know little about how these two events are coupled. Using the 3D co-culture model of mammary epithelial cells and monocytes, a recent study reveals a link between disruption of epithelial polar...

We consider the reliable multi configuration capacitated logistics network design problem (RMCLNDP) with system disruptions, concerned with facilities locating, transportation links constructing, and also allocating their limited capacities to the customers in order to satisfy their demands with a minimum expected total cost (including locating costs, link constructing costs, as well as expecte...

Disruption Tolerant Networks (DTNs) are emerging solutions to networks that experience frequent partitions. In this paper, we study how to provide high-performance multicasting service in DTNs. We first investigate three basic DTN multicast approaches. We then develop a multicast mechanism based on on-demand path discovery and overall situation awareness of link availability (OS-multicast) to a...

Major disruption to a transportation network can disturb traffic flow patterns significantly. To deploy effective and efficient traffic restoration projects, a good prediction of the traffic flow pattern under network disruption is vital. Although traffic flow evolution processes have been modeled in various ways in the literature, very limited attention has been paid to the traffic flow evolut...