objective: there is some evidence that chronic skin diseases like dermatitis could affect the quality of life of sufferers. in addition, patients with dermatological disorders are at greater risk to develop psychiatric morbidity. the aim of this study was to explore the quality of life in patients with chronic eczematous dermatitis. we also examined the effect of a convenient dermatologic inter...

Besides being an uncommon clinicopathological entity, interstitial granulomatous dermatitis, also described as interstitial granulomatous dermatitis with arthritis (IGDA), has shown a wide spectrum of clinical manifestations, such as linear and erythematous lesions, papules, plaques and nodules. Histological features include dense dermal histiocytic infiltrate, usually in a palisade configurati...

Pemphigus herpetiformis is an autoimmune bullous disease, that combines clinical features of dermatitis herpetiformis and linear IgA bullous dermatosis and immunological characteristics of pemphigus, which makes this disease peculiar and this diagnosis rarely suspected in the first evaluation of the patient. The reported case is of a patient with clinically bullous disease similar to dermatitis...

Purpose: Radiotherapy induced dermatitis is a common and sometimes serious side effect. We conducted a randomized study to understand whether the adjunctive use of aloe vera gel might reduce the prevalence and/or severity of radiotherapy induced dermatitis. Methods: One hundred patients with newly diagnosed breast cancer were randomized to receive aloe vera gel or nothing during adjuvant radiot...

Background: Vulvar contact dermatitis is inflammatory disorders of genital skin causing itch, burning, and plaques with overlying excoriation and linear fissures. Objective: To assess the effectiveness of a soft foam based on Tiab® system (TF), complex of titanium micro crystals covalently bound with silver ions associated with hyaluronic acid, as a treatment of vulvar contact dermatitis. Metho...

OBJECTIVE Coeliac disease (CD) is associated with immune-mediated skin diseases such as dermatitis herpetiformis and others. The objective of the study was to investigate the relation of body mass index (BMI), as an index of absorptive status, with the prevalence of skin diseases in adults with untreated CD. METHODS Anthropometry, gastro-intestinal symptoms, nutritional indices and immune-med...

introduction cement has a wide industrial usage and it is the leading cause of occupational skin diseases among construction workers, which are present as contact urticarial and contact dermatitis. case presentation a 79-year-old water sewage worker man referred to our department with numerous symmetric hyper-keratotic papules with an erythematous base on both hands and feet for about 20 years....

background: atopic dermatitis is a major public health problem, often starting in early childhood and sometimes followed by other allergic diseases. although hypersensitivity to foods is assumed to play an essential role in the development of atopic dermatitis in some patients, little is known about common food allergens in iranian children with atopic dermatitis. objectives: this study was des...

Linear epidermal nevi frequently follow the lines of Blaschko and may be confused with the verrucous stage of incontinentia pigmenti. Inflammatory epidermal nevus appears as a line array of pink to red papules usually on the lower limb (Buttock and hip) clinically resembling psoriasis or eczematous dermatitis. But inflammatory epidermal nevus has distinct histopathologic features. We report a c...

Mice deficient in SHARPIN (Sharpincpdm mice), a member of linear ubiquitin chain assembly complex (LUBAC), develop severe dermatitis associated with systemic inflammation. Previous studies have demonstrated that components of the TNF-signaling pathway, NLRP3 inflammasome and IL-1R signaling are required to provoke skin inflammation in Sharpincpdm mice. However, whether IL-1α or IL-1β, both of w...