The present investigation was carried out to estimate the effect of bioactive compound limonin on various biological enzymes like Glycogen; Membrane bound ATPases, Carbohydrate metabolizing enzymes and Mitochondrial TCA cycle enzymes against N-nitrosodiethylamine (DEN) induced primary liver cancer in male Wistar albino rats. Liver cancer was induced by single intraperitonial injection of DEN (2...

The influence of rootstock, maturity and extraction settings on limonin, hesperidin narirutin levels orange juice was evaluated. A liquid chromatographic method to determine limonin developed validated. linear range 0.410 61.5 µg.mL-1, with a correlation coefficient higher than 0.999. limit detection 0.144 µg.mL-1and quantification 0.363 µg; precision showed RSD≤5.0% accuracy from 92.6 100.4%. ...

Limonoids are highly oxygenated C13α-triterpenes and common secondary metabolites. Several hundred congeners have been isolated to date. The first total synthesis of (±)-limonin, the flagship congener of the limonoids, is now reported and features 1) a tandem radical cyclization generating the BCD ring system with the C13α configuration that is essential to the limonoids and a Robinson annulati...

Sixteen volatile compounds were identified from the n-hexane extract of the buds of Syzygium aromaticum by using gas chromatography-mass spectroscopy (GC-MS). The major components were eugenol (71.56 %) and eugenol acetate (8.99 %). The dichloromethane extract of the buds yielded limonin and ferulic aldehyde, along with eugenol. The flavonoids tamarixetin 3-O-b-D-glucopyranoside, ombuin 3-O-b-D...

BACKGROUND Development of insecticide resistance occurred due to the continuous and misuse of synthetic insecticides therefore, the recent study was conducted to explore eco-friendly plant extracts that have some potential to suppress mosquito larval population. METHODS WHO recommended mosquito larval bioassay method for insecticide was used while for the analysis of citrus oils for limonin a...

Four new limonoid derivatives, 1-O-methylichangensin (1), sudachinoid A (2), B (3), and C (4) were isolated from the seeds of Citrus sudachi, together with the known compounds ichangensin, obacunone, obacunoic acid and limonin, and the structures of the new compounds were elucidated based on spectroscopic and chemical evidence.

The seeds of Citrus reticulata afforded the new limonoid derivative, isolimonexic acid methyl ether, in addition to the previously isolated limonin, deacetylnomilin, obacunone and ichangin. The structure elucidation was achieved primarily through 1D and 2-D-NMR analyses. The marginal antimalarial activity of isolimonexic acid methyl ether is reported.