A 51-year-old female developed linear-like scleroderma in the left thigh following a linear wound caused by a car accident. 27 years later she also developed a typical diffuse cutaneous systemic sclerosis with extensive skin involvement and bibasilar pulmonary fibrosis. The second case is a 39-year-old female who had a history of Raynaud's phenomenon since early childhood. She developed a morph...

Sir, Hypertrichosis, an increase in non-androgen-modulated hair on the body, may be congenital or acquired, localized or generalized. It may be limited to cosmetic signi®cance or may represent a cutaneous sign of underlying systemic disease (1). There are a few reports of hypertrichosis on the indurated skin in melorheostotic scleroderma (2 ± 4). We describe here a 12-year-old Korean boy with l...

Skin tumors occurring on the scleroderma fingers are rarely seen. Swollen fingers are hallmarks of systemic sclerosis, and mucin deposition in the lesional skin is a constant feature in systemic sclerosis. Here we describe a case of cutaneous myxoid cyst on the flexor aspect of the sclerotic fingers in a patient with severe diffuse cutaneous systemic sclerosis. Cutaneous myxoid cyst is a relati...

The pathogenesis of scleroderma encompasses vascular, immunological, and fibrotic processes, which contribute to clinical manifestations. We investigated the prevalence of anti-annexin V IgG and IgM antibodies in sera of scleroderma patients and their relation to the presence of other antibodies and development of disease morbidity. Sera of 40 scleroderma patients and 15 healthy controls were e...

Systemic sclerosis (scleroderma; SSc) is divided further into limited cutaneous disease and diffuse cutaneous disease on the basis of the extent of skin thickening. Limited disease is defi ned as skin thickening that only affects the extremities below the elbows and/or below the knees. Diffuse cutaneous disease is defi ned as skin thickening proximal to the elbows/or knees in addition to distal...

Calcinosis is a well-recognized manifestation of systemic sclerosis. Paraspinal or intraspinal calcinosis is rare, with reports of calcinosis involving the cervical, thoracic and lumbar separately, but not together. We now report a case of limited cutaneous scleroderma with extensive paraspinal calcinosis of the cervical and lumbar spine.