BACKGROUND Thermal injury is associated with several biochemical and histopathological alteration in tissue. Analysis of these objective parameters in research and clinical field are common to determine healing rate of burn wound. Negative pressure wound therapy has been achieved wide success in treating chronic wounds. This study determines superficial burn wound healing with intermittent nega...

Aim: Emerging evidence favors the important role of antioxidants, matrix metalloproteinases (MMPs), and nitric oxide (NO) in the healing of diabetic wounds. There is a lack of substantial evidence regarding the effects of negative pressure on antioxidants, MMPs and NO in chronic wounds associated with diabetes. Methods: A total of 55 type 2 diabetic patients with leg ulcers were divided into 2 ...

Aim: Changes in the pH of chronic wounds can inhibit the optimal activity of various enzymes in the wound environment, thereby delaying wound healing. The aim of the present study is to monitor the effect of limited access dressing (LAD) on the pH on the surface of chronic wounds. Methods: A total of 140 patients with chronic wounds of more than 4 weeks duration were divided into two groups by ...

Aim: Negative pressure wound therapy (NPWT) has achieved widespread success in the treatment of chronic wounds. However, its effects have been only partially explored, and investigations have generally concentrated on the wound‐dressing interface; a detailed histopathological description of the evolution of wounds under NPWT is still lacking. The present study was performed to investigate the e...

Background: Common measures to stop bleeding can run the risk of clotting and thrombosis due to prolonged application of pressure. Topical homeostatic agents have an important role in decreasing time to hemostasis and consequently prevention of the complications.   Aim: the aim of this study was to compare Celox powder and conventional bandage on time to hemostasis in the vascular access site i...