Fipronil is an insecticide widely used in agriculture, veterinary medicine and public health that has recently been listed as a potential endocrine disrupter. In the present study we evaluated the effects of perinatal exposure to fipronil during the period of sexual brain differentiation and its later repercussions on reproductive parameters in male rats. Pregnant rats were exposed (via gavage)...

OBJECTIVE Dexmedetomidine is an α-2 adrenergic agonist having wide range of effects including sedation in mammalian brain, and has analgesic as well as sympatholytic properties. This study aimed to compare the effects of dexmedetomidine and propofol infusion on sedation characteristics in patients undergoing combined sciatic nerve and femoral nerve block via anterior approach for lower limb ort...

Caffeine is consumed by over 80% of U.S. adults. This review examines the effects caffeine has on cognitive and physical function, since most real-world activities require complex decision making, motor processing and movement. Caffeine exerts its effects by blocking adenosine receptors. Following low (∼40mg or ∼0.5mgkg-1) to moderate (∼300mg or 4mgkg-1) caffeine doses, alertness, vigilance, at...

the purpose of this project is the investigation of lhrha2 integrated effect with carp pituitary extract (cpe) in three stages injection on sexual indexes (fecundity, fertilization, hatch and larval survival) in artificial propagation of barbusxanthopterus. 20 fish were divided in to 4 treatment and injected interpritoneal as follows 4mgkg-1b.w.of cpe as positive control, 4 µg/kg +4 mgkg-1b.w. ...

The purpose of this project is the investigation of LHRHa2 integrated effect with carp pituitary extract (CPE) in three stages injection on sexual indexes (fecundity, fertilization, hatch and larval survival) in artificial propagation of Barbusxanthopterus. 20 fish were divided in to 4 treatment and injected interpritoneal as follows 4mgkg-1b.w.of CPE as positive control, 4 µg/kg +4 mgkg-1b.w. ...