Background: Langerhans cells are important in the pathogenesis of leprosy.  A recent study reported that these cells were almost absent in the epidermis overlying lepromatous lesions. Objective: To investigate a possible relationship between the number of Langerhans cells and the histopathologic spectrum of lesions in patients with leprosy. Methods: An immunohistochemical staining for S100 prot...

histoid leprosy (hl) is a rare variant of lepromatous leprosy, occurring in long-standing cases, mostly in a background of acquired drug resistance. patients usually present with sudden onset multiple nodules and plaques, most often involving the skin and subcutaneous tissue of trunk and lower limbs. here we report an unusual case of de novo (without any history of prior anti-leprotic therapy) ...

Erythema Nodosum Leprosum (ENL) reaction is a serious and common complication of multibacillary leprosy. Thalidomide an effective drug which can be used safely in the treatment ENL, with due regard to its teratogenic potential. In many leprosy-endemic countries it still not available leprologists. this editorial we discuss hindrance access thalidomide, some considerations as how ensure safe use...

background: despite significant reduction in global disease prevalence, leprosy still has a high rate of disability while its determinants are unfair and many of them are amendable. the objective of this study was to measure inequality of disability in leprosy in iran. methods: this was a cross‑sectional study (2006‑2007) on all living people affected by leprosy registered in w. azerbaijan prov...

purpose: to report a known case of leprosy with bilateral corneal scars. case report: we present a 70 year-old man who had developed claw hand deformity and loss of sensation in the extremities secondary to leprosy since 7 years ago. two years ago, he presented with loss of vision due to lagopthalmos and loss of corneal sensation for which he had undergone lateral tarsorrhaphy at the time. conc...

leprosy is one of the oldest diseases of the country and may have been brought over to this country from egypt in ancient times. leprosy is mose frequent in the province of tehran, east azarbaijan, guilan and mazandaran (43 per km2) than other part of the country (13-18 per km2).the incidence of leprosy is recorded at 7.7 per thousand and 35.2 per thousand in the southern and northern part of t...

Leprosy, also known as Hansen’s disease, is caused by the bacterium Mycobacterium leprae. This disease attacks skin, peripheral nerves, upper respiratory tract mucosa and eyes. undergoes a long division process between 2-3 weeks. The survival of leprosy bacteria 9 days outside human body. Leprosy germs have an incubation period 2-5 years. World Health Organization reported that in 2019, 202,256...

To support the achievement of global leprosy targets, there is a need for improved data management and mapping. At 2022 International Leprosy Congress, Global Mapping Initiative was announced with goal to develop tools, processes, best practices ministries health map leprosy, focus on capacity building, sustainability, knowledge exchange facilitate targets. This initiative will build lessons le...

We thank Jan Richardus and colleagues for their feasibility study of single-dose rifampicin contacts individuals diagnosed with leprosy.1 Single-dose was incorporated into the WHO Guidelines Diagnosis, Treatment Prevention Leprosy as a conditional recommendation based on moderate evidence.2 The roadmap neglected tropical diseases 2021–30 targets leprosy elimination (interruption transmission) “...