conclusions l. major is the main species responsible for cutaneous leishmsniasis in four geographical regions of khuzestan province southwestern of iran and nested pcr can be used for diagnosis and leishmania species identification. results 138 (94.5%) out of 146 cases of four regions were l. major and 8(5.5%) were l. tropica. 57.97% of l. major cases were male and 42.03% were female. 87.5% of ...

BACKGROUND The development of polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique for species identification among patients presenting leishmaniasis allowed to better determine the main circulating species in French Guiana. METHODS A descriptive study of the Leishmania species was identified, and their spatiotemporal distribution was conducted using patient...

BACKGROUND Three major forms of human disease, cutaneous leishmaniasis, visceral leishmaniasis and mucocutaneous leishmaniasis, are caused by several leishmanial species whose geographic distribution frequently overlaps. These Leishmania species have diverse reservoir hosts, sand fly vectors and transmission patterns. In the Old World, the main parasite species responsible for leishmaniasis are...

Introduction: Cutaneous leishmaniasis (CL) is an increasing public health problem in several parts of Iran. In southern parts, the incidence of CL has been doubled over the last decade. This epidemiological study was done for determination of reservoir(s) and vector(s) of cutaneous leishmaniasis in rural regions of Marvdasht, Fars province,southern Iran during 2003 and 2004. Methods: A total of...

background: leishmaniasis is a zoonotic disease caused by species of protozoa of the genus leishmania . in recent years, incidence of cutaneous leishmaniasis has increasing trend in golestan province, north of iran. the aim of the present study was to identify the frequency of cutaneous leishmaniasis using pcr-rflp in patients referred to kalaleh health center, during 2013-14. methods: this des...

Leishmaniasis is a wide-spectrum disease caused by parasites from Leishmania genus. A well-modulated immune response that established after the long-lasting clinical cure of leishmaniasis can represent standard requirement for vaccine. Previous studies demonstrated (Viannia) naiffi causes benign and its antigens induce responses in vitro. In this work we aimed to identify immunodominant protein...

Clinical manifestations of leishmaniasis are diverse and related to the infecting species, its relationship with the environment and the host immune response. A case of late Andean cutaneous leishmaniasis with extensive manifestation is presented. The case was confirmed through microbiological and immunological studies; identification was performed by cytochrome b gene sequencing and the specie...

BACKGROUND & OBJECTIVES The recently recognized endemic focus of leishmaniasis in Satluj river valley in Himachal Pradesh (India) lies in north-western Himalayas (30 degrees N, 70 degrees E). This endemic focus of leishmaniasis appears peculiar where localized cutaneous leishmaniasis (LCL) co-exists with visceral leishmaniasis (VL), and Leishmania donovani is predominant pathogen for LCL wherea...