A latex particle agglutination test is described which is suitable for the recognition of heat-labile enterotoxin-producing colonies of Escherichia coli immediately after primary culture on a variety of commonly used enteric diagnostic media. The test is simple and economical to perform, and the results are available in minutes.

A new serological technique of diagnosing human hydatid disease, employing polystyrene latex particles coated with hydatid cyst fluid, and a modified technique using bentonite particles are described. Comparison of the latex test with the complement-fixation test performed on 102 sera has shown a total agreement of 98% and an agreement of 93.1% in the positive specimens. The bentonite test and ...

Synopsis A short history of the laboratory diagnosis of pregnancy is followed by an evaulation of four immunological methods of pregnancy diagnosis. The immunological methods based upon haemagglutination-inhibition and slide latex agglutination, gave a.lOO% accuracy. It is concluded that these techniques are suitable for the diagnosis of pregnancy after the 35th day following the last menstrual...

A new enzyme immunoassay (Rubenostika; Organon Teknika, Turnhout, Belgium), a new latex agglutination test (Rubalex; Orion Diagnostica, Espoo, Finland), and three other accepted methods for the determination of rubella immunity were compared with a standard hemagglutination inhibition assay. Of 224 serum samples tested, 54 (24%) were nonreactive and 24 (11%) were low titered. All procedures wer...

A latex agglutination test was evaluated as a method for detection and titration of antiplague antibodies. Slide and microtiter techniques using polystyrene latex particles coated with specific fraction-I-antigen of Yersinia pestis were found to be comparable in specificity and sensitivity to serological tests commonly used in laboratory practice. The latex agglutination titers correlated well ...

The cryptococcal antigen lateral flow assay (CrAg LFA) was evaluated for the diagnosis of cryptococcosis in HIV-negative patients. The sensitivity was excellent, suggesting that this assay can replace conventional testing based on latex agglutination (LA). CrAg LFA and LA titers were correlated but were not directly comparable, with implications for conversion between assays.

Sera from 48 Kenyan Africans with rheumatoid arthritis, 43 patients with other diseases, and 98 blood donors were tested for the presence of rheumatoid factor by latex fixation tests using human European, human African, and rabbit immunoglobulin, and a sheep cell haemagglutination test. In the patients with rheumatoid arthritis the frequency of rheumatoid factor was comparable to that reported ...

Five groups of strains of Staphylococcus aureus (54 in total) were tested by slide and tube coagulase methods with rabbit and human plasma, and the results were compared with a latex test for both clumping factor and Protein A (Staphaurex, Wellcome Foundation). The five groups comprised: epidemic methicillin resistant S aureus (group 1); other methicillin resistant S aureus (group 2); other res...

A new latex agglutination test for rubella virus was used to test sera with a hemagglutination inhibition titer of -8 (97 specimens) or >256 (158 specimens). Maximum latex agglutination test sensitivity was achieved when low-titer sera were tested undiluted and high-titer sera were diluted (1:10). A modification of the protocol of the manufacturer resulted in a latex agglutination-hemagglutinat...

OBJECTIVE To determine the diagnostic and prognostic test qualities of the enzyme linked immunosorbent assays (ELISA) for rheumatoid factor isotypes in rheumatoid arthritis (RA), and to compare them with the latex fixation test. METHODS Rheumatoid factor tests were performed in 1988 consecutive new rheumatology outpatients within two months after their first visit to the outpatient clinic of ...