exacerbation of the adrenal insufficiency with return of anorexia, lassitude, loss of weight, and low blood pressure. Although patients with Addison's disease, treated with cortisone, are not usually hypersensitive to insulin, in this present case, as the patient's condition improved satisfactorily, and her insulin sensitivity was uncertain, the latter drug was not used immediately. It is inter...

Junior Medical Officer, Haddo, Port Blair. The following two cases of post-enteric complications are, I think, of sufficient interest to justify publication. They are also far from being common sequels. Case No. 1.?The first was a case of a left parotid abscess in a female patient. Her history was of fever of a month's duration with a persistent diarrhoea of loose yellow motions, constant heada...

Influenza infection causes fever, sore throat, muscle pains, cough, lassitude and headache. Annual attack rates average 10% to 20%, but may be higher during severe epidemics. Malaise following influenza can persist for several weeks. Morbidity and mortality, associated with influenza, are usually more common in the older population and in individuals with significant concurrent medical problems...

This study examined the reliability and validity of an expanded version of the Iowa Sleep Disturbances Inventory (ISDI; Koffel & Watson, 2010) in 2 samples (219 college students and 200 psychiatric patients). The expanded ISDI includes the scales Sleep Paralysis and Sleep Hallucinations. These scales, along with the Nightmares scale, help define a higher order factor entitled Unusual Sleep Expe...

OBJECTIVE To assess the associations between psychological factors and return to work among long-term sickness absentees. DESIGN Longitudinal study with a 3-year follow-up. SUBJECTS Long-term sickness absentees (n = 905) who had undergone a multidisciplinary medical assessment. METHODS Three years after multidisciplinary medical assessment, return to work status (full, partial, or none) w...

The aim of this study was to evaluate the effects of levomilnacipran extended-release (ER) on depression-related fatigue in adults with major depressive disorder. Post-hoc analyses of five phase III trials were carried out, with evaluation of fatigue symptoms based on score changes in four items: Montgomery-Åsberg Depression Rating Scale (MADRS) item 7 (lassitude), and 17-item Hamilton Depressi...

Low plasma potassium level can cause muscle weakness, lassitude, constipation as well as rhabdomyolysis and arrhythmias, when severe. In muscle, low plasma potassium increases resting membrane potential (hyperpolarization) of myocytes that tend to make muscle more refractory to excitation, leading to muscle weakness. Hypokalemia can be associated with a myriad of causes including drugs of abuse...

BACKGROUND Females are twice as likely as males to experience depression. Recent findings indicate a relationship linking inflammation with depression. Whether the higher prevalence of depression in women is sex-specific or if inflammation contributes to a higher prevalence of depression in females is unclear. Thus, the objective was to determine whether depressed females show higher inflammati...

BACKGROUND Motor symptoms form the hallmark of Parkinson's Disease (PD), although features like depression are often present. Depression rating scales [e.g. Montgomery-Asberg Depression Rating Scale (MADRS)] used in PD measure affective, cognitive and somatic symptoms. An important clinical question is which items of the MADRS are likely to be influenced by PD symptoms. METHODS Depression was...

The beneficial effects of the X-rays in the treatment of leukaemia are now well known ; unfortunately, they do not seem to be permanent. Although a cure is not to be expected, very decided improvement results for a considerable time. Cases of myeloid leukaemia do best. The most striking effect of the X-rays is a rapid reduction of the number of white cells, especially of myelocytes, in the bloo...