We consider a class of a nested optimization problems involving inner and outer objectives. We observe that by taking into explicit account the optimization dynamics for the inner objective it is possible to derive a general framework that unifies gradient-based hyperparameter optimization and meta-learning (or learning-to-learn). Depending on the specific setting, the variables of the outer ob...

objective(s):neurotoxicity of anticancer drugs complicates treatment of cancer patients. vinblastine (vbl) is reported to induce motor and cognitive impairments in patients receiving chronic low-dose regimen. materials and methods: the effects of vbl treatment on motor, learning and memory functions of male and female wistar rats were studied by behavioral related tests. animals were given chro...

ABSTRAKKurikulum merdeka belajar merupakan proses pembelajaran di mana guru dan siswa diberi kebebasan dalam menggali pengetahuan keterampilan lingkungannya untuk meningkatkan kualitas sumber daya manusia yang sesuai dengan profil pelajar Pancasila, sehingga dapat bersaing dunia perkembangan zaman, sebagai bekal kerja pada era 5.0. Tujuannya menjelaskan model project-based learning berpikir kri...

diabetes mellitus is accompanied with disturbances in learning, memory, and cognitive skills in the humans and experimental animals. due to the anti-diabetic and antioxidant activity of pelargonidin (pg), this research study was conducted to evaluate the efficacy of chronic oral pg on alleviating learning and memory disturbance in streptozotocin-diabetic rats. male wistar rats were divided into...