The purpose of this study was to use cation exchange resins mask Pregabalin's unpleasant taste. Dowex-50, a crosslinked polystyrene backbone, employed. DRCs were synthesised in batches with drug-to-resin ratios 1:1, 1:2, and 1:3. optimal ratio as well the time required for maximum complexation discovered. In work, an attempt made develop taste-masked Pregabalin solution using simple, rapid, cos...

The demand for mouth dissolving tablets has been growing, during the last decade especially for geriatric and pediatric patients because of swallowing difficulties. The purpose of this research was to mask the intensely bitter taste of Ondansetron HCl and to formulate a orodispersible of the taste-masked drug. Taste masking was done by complexing Ondansetron HCl with Kyron T-134 in different ra...

The purpose of this investigation is to formulate and evaluate the antihypertensive drug propranolol hydrochloride sustained-release bilayer tablets. In formulation, one layer provides a loading dose through immediate release other maintenance for up 12 h controlled release. Different quantities polymers such as Kyron T-314, Hydroxypropyl methylcellulose- K4M, ethyl cellulose were used make bi-...

Sildenafil citrate is one of the most effective agents for treatment of erectile dysfunction which acts by inhibiting the cGMP-specific phosphodiesterase type 5. Extensive research work is focused on flash release dosage forms and especially fast dissolving films are successful to attract pharma-industry due to ease of preparation and opportunity to extend patent life. Films are widely acceptab...

In the present investigation, a novel multifunctional co-processed superdisintegrants consisting of crospovidone and Kyron T-314 were fabricated by solvent evaporation method to develop melt-in-mouth tablets of metoclopramide hydrochloride with a view to enhance patient compliance by direct compression method. The simple physical blends and co-processed mixture of superdisintegrants were charac...

A 15-year old female Rothschild Giraffe (Giraffa camelopardalis rothschildi) weighing approximately 800kg, at the African Fund for Endangered Wildlife (AFEW), Giraffe Center, Langata, Nairobi, Kenya was presented with dystocia in June 2010. This giraffe named Laura, had a protracted labor and was regularly monitored by sanctuary education rd staff. Dystocia was relieved on the 3 day at this wil...

A sterilised, female calico domestic cat, weighing 4 kg, was presented to a private practitioner for examination. Her mother had produced her first and only litter, comprising 6 kittens, at the age of 3 years. Apart from this particular cat, all of the kittens appeared to be normal. The cat presented appeared to have no problems apart from the structure of her right forelimb, which she did not ...