INTRODUCTION Rhinoscleroma is a chronic granulomatous infection of the respiratory tract due to Klebsiella rhinoscleromatis (K. rhinoscleromatis). PATIENTS AND METHOD We observed two cases of rhinoscleroma in the Souro-Sanou university hospital of Bobo-Dioulasso, Burkina Faso, over a 9-year period (2009 to 2010). RESULTS A 19-year-old man and a 38-year-old woman both consulted with obstruct...

T-lymphocyte subpopulations were studied in a group of patients with rhinoscleroma due to Klebsiella rhinoscleromatis. The data demonstrated that these patients had a significantly greater number of T-suppressor/cytotoxic lymphocytes than did clinically healthy individuals. This finding correlated with a diminished response to the T-cell mitogen concanavalin A. The evidence indicated that the T...

Rhinoscleroma is a chronic progressive granulomatous condition due to Klebsiella rhinoscleromatis.' In severe cases the typical nodular lesions may extend from the nasopharynx into the respiratory tract and be refractory to antibiotics. We are currently investigating the use of laser treatment for lesions in the trachea and major bronchi.2 Such treatment is applicable to benign and malignant le...

OBJECTIVE To incorporate the first polymerase chain reaction (PCR) assay for Calymmatobacterium granulomatis into a colorimetric detection system for use in routine diagnostic laboratories. METHODS A capture oligonucleotide specific for the Klebsiella phoE gene was covalently linked to tosyl activated magnetic beads. Biotinylated phoE PCR products obtained from 14 positive specimens from pati...

Different Klebsiella species may vary with the type of infections they cause in both the community and hospital environments. However, in many laboratories in developing countries, differentiation of the genus Klebsiella into species is not generally done during bacteriological diagnosis due to high cost and special skills involved. This study aimed at determining the prevalence of different Kl...

A 39 year-old man came to our institution because of a five-year history of a progressive painful growing mass on his left nostril, which cause airway obstruction with ulceration. Because of a suspicion of malignancy, surgery (mass resection and subtotal nasal reconstruction) was performed. Histologic samples ruled out malignancy, and tissue cultures for fungus and mycobacteria were negative, b...

Aerobic and microaerobic diazotrophs possess numerous oxygen restriction strategies to protect nitrogenase from inactivation by oxygen without interfering with energy generation through oxidative phosphorylation. Protection by conformational change in nitrogenase was first detected and described in Azotobacter. This strategy once considerd unique for Azotobacter has been shown in this study to ...